Search for dissertations about: "Carl-henrik Heldin"
Showing result 1 - 5 of 32 swedish dissertations containing the words Carl-henrik Heldin.
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1. Regulation of Hyaluronan Synthesis and Signaling via CD44 in Cancer
Abstract : Hyaluronan is a ubiquitous glycosaminoglycan which is an important constituent of the extracellular matrix (ECM). In addition to organizing the extracellular matrix and regulating tissue homeostasis, hyaluronan, by binding to its main cell surface receptor CD44, is involved in intracellular signaling pathways regulating major cellular processes during development, wound healing, inflammation and cancer. READ MORE
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2. Studies on growth factors for human cultured cells
Abstract : .... READ MORE
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3. Experimental Studies of BMP Signalling in Neuronal Cells
Abstract : The developing nervous system depends largely on extracellular cues to shape its complex network of neurons. Classically, neurotrophins are known to be important mediators in this process. READ MORE
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4. Studies on the biological functions of interaction between components in Wnt, TGF-β and HIF pathways for cancer progression
Abstract : Cancer is a disease that involves aggressive changes in the genome and aberrant signals between the living cells. Signalling pathways such as TGF-β (Transforming growth factor-β), Wnt, EGF (epidermal growth factor) and HIF (Hypoxia-inducible factor) evolved to regulate growth and development in mammals. READ MORE
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5. Epigenetic Regulation of Replication Timing and Signal Transduction
Abstract : Upon fertilization the paternal and maternal genomes unite, giving rise to the embryo, with its unique genetic code. All cells in the human body are derived from the fertilized ovum: hence they all contain (with a few exceptions) the same genetic composition. READ MORE