Search for dissertations about: "Caroline Grabbe"

Found 2 swedish dissertations containing the words Caroline Grabbe.

  2. 1. Protein tyrosine kinases and the regulation of signalling and adhesion in drosophila melanogaster

    Author : Caroline Grabbe; Ruth Palmer; Tapio Heino; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Drosophila; Signalling; Adhesion; Protein Tyrosine Kinase; Development; Endocytosis; Molecular biology; Molekylärbiologi;

    Abstract : In order to build a multi-cellular organism and to regulate cellular functions, cells need to communicate with each other, as well as tightly regulate their behaviour in response to environmental changes. For these purposes all eukaryotic cells express a large number of membrane spanning receptors that either themselves contain catalytic activity or via cytoplasmic effector enzymes, function to transmit “signals” from the cell exterior to induce appropriate responses within the cell. READ MORE

  4. 2. Function and targets of the Urm1/Uba4 conjugation machinery in Drosophila melanogaster

    Author : Behzad Khoshnood; Caroline Grabbe; Tor Erik Rusten; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Drosophila; Urm1; Uba4; MOCS3; Tax; HTLV; Posttranslational modification; ubiquitin-like modifiers; UBL; PTM; JNK; neuromuscular junctions; signaling; molekylärbiologi; Molecular Biology;

    Abstract : Posttranslational modification (PTM) of proteins is essential to maintain homeostasis and viability in all eukaryotic cells. Hence, besides the sequence and 3D folding of a polypeptide, modification by multiple types of PTMs, ranging from small molecular groups to entire protein modules, adds another layer of complexity to protein function and regulation. READ MORE