Search for dissertations about: "Cartilage"

Showing result 21 - 25 of 256 swedish dissertations containing the word Cartilage.

  2. 21. Engineering Nanotherapeutic Strategies for Osteoarthritis Treatment

    Author : Ula von Mentzer; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; nanoparticles; nanomedicine; cartilage; osteoarthritis;

    Abstract : Osteoarthritis (OA), the most prevalent joint disorder, is characterized by the degeneration of cartilage tissue leading to pain, stiffness, and impaired mobility. Primarily affecting the elderly, OA can also impact athletes, postmenopausal women, and individuals with conditions like diabetes. READ MORE

  4. 22. Joint disease biomarkers - discovery and application

    Author : Dovilė Sinkevičiūtė; Reumatologi och molekylär skelettbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Osteoarthritis; Psoriatic arthritis; cartilage; Proteomics; Biomarkers; ELISA; Tissue culture; Extracellular matrix ECM ;

    Abstract : Dysregulated cartilage homeostasis, articular cartilage degradation and abnormal bone remodeling are common denominators in joint disease and can lead to severe disability for the patients. The molecular pathways behind the disease pathology can overlap across different joint diseases. READ MORE

  5. 23. The collagen fibrillar network: Sequential degradation of its constituents by tissue metalloproteinases

    Author : Terrence Heathfield; Enheten för led- och mjukvävnadsforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; metabolism; Metabolism; Biochemistry; collagen; fibromodulin; cartilage; osteoarthritis; Biokemi;

    Abstract : The cartilage matrix is made up of a fibrillar meshwork comprising type II collagen and other associated proteins. One main function of this network is to retain the large aggregating proteoglycan, aggrecan, a vital component in the regulation of fluid flux in cartilage. READ MORE

  6. 24. Promoting the Clinical Relevance of 3D Bioprinting

    Author : Peter Apelgren; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 3D Bioprinting; Cartilage;

    Abstract : This thesis focuses on the development of methodologies enabling the reconstruction of autologous, functional, and long-term-stable cartilage-like tissue using 3D bioprinting technology and animal experiments. The stability, resilience, and in vivo viability of the printed cells and tissue vascularization, as well as the observed immunogenicity and safety, represent the main issues evaluated and discussed in this thesis. READ MORE

  7. 25. Studies on chondroadherin-an extracellular matrix leucine-rich repeat protein

    Author : Christina Wenglén; Reumatologi och molekylär skelettbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk biologi; Clinical biology; COMP; SLRP; ECM; collagen; cartilage; chondroadherin;

    Abstract : This thesis describes chondroadherin, one of the leucine-rich repeat proteins in the extracellular matrix (ECM) of cartilage. Chondroadherin defines a subgroup of its own by not having an N-terminal extension, having a different cysteine pattern and by being devoid of carbohydrate substitutions. READ MORE