Search for dissertations about: "Cas"

Showing result 1 - 5 of 72 swedish dissertations containing the word Cas.

  1. 1. The type I-E CRISPR-Cas system Biology and applications of an adaptive immune system in bacteria

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Lina Amlinger; Uppsala universitet.; [2017]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; CRISPR; CRISPR-Cas; virus defense; bacteria; bacteriophage; adaptation; spacer integration; interference; gene silencing; fluorescent reporter; Escherichia coli; Mikrobiologi; Microbiology;

    Abstract : CRISPR-Cas systems are adaptive immune systems in bacteria and archaea, consisting of a clustered regularly interspaced short palindromic repeats (CRISPR) array and CRISPR associated (Cas) proteins. In this work, the type I-E CRISPR-Cas system of Escherichia coli was studied.CRISPR-Cas immunity is divided into three stages. READ MORE

  2. 2. Parameters influencing inclusion compositions in Al-killed steel melts during a secondary refining process

    University dissertation from Stockholm : KTH Royal Institute of Technology

    Author : Takanori Yoshioka; KTH.; [2018]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; non-metallic inclusion; ladle furnace; RH; thermodynamics; contact angle; Al2O3; MgO•Al2O3 spinel; calcium aluminate; CaS.;

    Abstract :      This study was carried out to clarify the factors influencing the evolution of inclusions in Al-killed steel melts during a secondary refining process. First, a case-hardening steel was the subject of study to understand the factors influencing the inclusion compositions in the steel melt. READ MORE

  3. 3. Antiphagocytosis by Yersinia pseudotuberculosis role of the YopH target proteins

    University dissertation from Umeå : Molekylärbiologi

    Author : Ming Yuan; Umeå universitet.; [2006]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Molecular biology; Cas; Fyb; mAbp1; SKAP-HOM; Yersinia pseudotuberculosis; YopH; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Abstract : The enteropathogenic bacterium Yersinia pseudotuberculosis binds to β1 integrins on a host cell via its surface protein invasin. This event stimulates signal transduction to the actin cytoskeleton of the eukaryotic cell, which allows the cell to engulf the bacterium that is attached to its surface. However, the pathogen Y. READ MORE

  4. 4. Studies on the transmembrane signaling of β1 integrins

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Annika Armulik; Uppsala universitet.; [2000]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Integrin β1; signaling; transmembrane domain; CAS; focal adhesion kinase; Biokemi; MEDICINE Chemistry Biochemistry; MEDICIN Kemi Biokemi; Medical Biochemistry; medicinsk biokemi;

    Abstract : Integrins are heterodimeric cell surface receptors, composed of an α and a β subunit, mainly binding for extracellular matrix proteins. lntegrin subunit β1 can combine with at least 12 a subunits and thus form the biggest subfamily within the integrin family. READ MORE

  5. 5. Small RNAs, Big Consequences Post-transcriptional Regulation and Adaptive Immunity in Bacteria

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Mirthe Hoekzema; Uppsala universitet.; [2018]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; small RNA; sRNA; non-coding RNA; Hfq; gene regulation; post-transcriptional regulation; biofilm; OmrA; OmrB; toxin-antitoxin; TisB; IstR-1; Persisters; CRISPR-Cas; CRISPR-Cas adaptation reporter; Escherichia coli; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

    Abstract : It is nowadays widely accepted that non-coding RNAs play important roles in post-transcriptional regulation of genes in all kingdoms of life. In bacteria, the largest group of RNA regulators are the small RNAs (sRNAs). READ MORE