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Showing result 1 - 5 of 443 swedish dissertations matching the above criteria.

  1. 1. Molecular epidemiology approach : nested case-control studies in glioma and lymphoid malignancies

    Author : Florentin Späth; Beatrice S. Melin; Carl Wibom; Ann Sofie Johansson; Ingvar Bergdahl; Ola Landgren; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glioma; B cell lymphoma; multiple myeloma; risk; repeated samples; prospective longitudinal study; nested case-control study; circulating sEGFR and sERBB2; circulating immune markers and growth factors; marker disease association; disease progression; NSHDS; Janus; linear mixed modeling; epidemiologi; Epidemiology; Oncology; onkologi;

    Abstract : BACKGROUND: Nested case-control studies aim to link molecular markers with a certain outcome. Repeated prediagnostic samples may improve the evaluation of marker-disease associations. However, data regarding the benefit of repeated samples in such studies are sparse. READ MORE

  2. 2. On intestinal ischaemia after aortoiliac surgery : Epidemiological, clinical and experimental studies

    Author : Martin Björck; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Ischaemia; intestines; colon; ischaemic colitis; aorta-abdominal; aortic aneurysm-abdominal; aortic rupture; atherosclerosis; postoperative complications; cohort studies; case-control studies; clinical protocols; experimental design; incidence; risk factors; diagnosis; treatment outcome; intra-mucosal pH; pHi; swine; splanchnic circulation; haemodynamics; dobutamine; Kirurgi; Surgery; Kirurgi; Surgery; kirurgi;

    Abstract : An important cause of death among patients undergoing surgery of the abdominal aorta is intestinal ischaemia. In the Swedish Vascular Registry 2930 aortoiliac operations were identified. The complication was studied in a combined cohort and case-control study, and multivariate analysis performed. The incidence of intestinal ischaemia was 2. READ MORE

  3. 3. Efficient design and analysis of extended case-control studies

    Author : Bénédicte Delcoigne; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The nested case-control design is widely used in epidemiology for its efficiency, as it combines the advantages of both cohort and case-control designs. This design is an extension of the matched case-control design, where the matching variable is the time of occurrence of the outcome. READ MORE

  4. 4. Causal inference and case-control studies with applications related to childhood diabetes

    Author : Emma Persson; Ingeborg Waernbaum; Xavier de Luna; Gisela Dahlquist; Stijn Vansteelandt; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; covariate selection; design-weighted estimation; marginal effect; matching; register study; treatment effect; type 1 diabetes mellitus; Statistics; statistik;

    Abstract : This thesis contributes to the research area of causal inference, where estimation of the effect of a treatment on an outcome of interest is the main objective. Some aspects of the estimation of average causal effects in observational studies in general, and case-control studies in particular, are explored. READ MORE

  5. 5. Epidemiological Aspects of Asthma in Primary Care : Special Reference to Prevalence, Clinical Detection and Validation

    Author : Mikael Hasselgren; Gunnar Johansson; Staffan Janson; David Price; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Adult; Adolescent; Asthma; Case-Control Studies; Causality; Child; Cross-Sectional Studies; Diagnosis Computer-Assisted; Epidemiology; Prevalence; Primary Health Care; Validation Studies; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

    Abstract : Objectives. To describe the prevalence of asthma in a mid-Swedish region and measure the detection rate of asthma in primary care. To compare clinical outcomes for adolescents with asthma in primary care or in paediatric care and to perform a clinical validation in children with airway, nose and skin symptoms. Material and methods. READ MORE