Search for dissertations about: "Caudate-putamen"

Showing result 1 - 5 of 6 swedish dissertations containing the word Caudate-putamen.

  2. 1. Dopamine receptors in the rat brain

    Author : Mi Hillefors-Berglund; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Dopamine D2 receptors; Dopamine D3 receptors; Rat; Autoradiography; [3H]7-OH-DPAT; [3H]PD 128907; Caudate-putamen; Subcortical limbic area; Islands of Calleja; CGS 21680; Toluene; Neurotensin; Asphyxia; Aging; Magnesium; GTP;

    Abstract : Dopamine receptors belong to a large superfamily of G protein-coupled receptors and consist of the D1, D2, D3, D4, and D5 receptors. The D2, D3, and D4 receptors belong to the D2 receptor family which is characterized by having a large third cytoplasmic loop and a short C-terminus projecting into the cytosol, and by inhibiting the enzyme adenylyl cyclase. READ MORE

  4. 2. Anabolic androgenic steroids and central monoaminergic systems : Supratherapeutic doses of nandrolone decanoate affect dopamine and serotonin

    Author : Carolina Birgner; Lena Bergström; Anna Kindlundh-Högberg; Fred Nyberg; Stefan Brené; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; anabolic androgenic steroids; nandrolone decanoate; dopamine; serotonin; rat; central nervous system; Pharmacology; Farmakologi;

    Abstract : Supratherapeutic doses of anabolic androgenic steroids (AASs) are administered, not only as performance-enhancing drugs in the world of sports, but also in order to modify behaviour. AAS abusers are at risk of developing serious physical and psychological side effects such as dependence and aggressive behaviour. READ MORE

  5. 3. Advanced Mass Spectrometry Imaging in Neuropharmacology

    Author : Theodosia Vallianatou; Per E. Andrén; Anna Nilsson; Mohammadreza Shariatgorji; Maria Karlgren; Irena Loryan; Nathalie Agar; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mass spectrometry imaging; neuropharmacology; blood brain barrier; drug-drug interactions; aging; tacrine;

    Abstract : Mass spectrometry imaging (MSI) has emerged as a valuable approach for mapping multiple molecular species in sections of diverse tissues. It enables simultaneous detection of numerous compounds (from neurotransmitters to small proteins) in the brain at relatively high lateral resolution (>5 μm) on a routine basis. READ MORE

  6. 4. A study of neuropeptide Y in brains of 'depressed' and healthy rats

    Author : Patricia A Jimenez Vasquez; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Neuropeptide Y; Depression; Animal Models of Depression Antidepressant treatments;

    Abstract : Neuropeptide Y (NPY), a 36-amino acid peptide that was originally isolated from mammalian brain tissue, is widely distributed in both rat and human brain. NPY has a number of physiological actions and affects for example hypothalamic-pituitary-adrenal (HPA)-axis and circadian rhythms, modulates memory processing and food intake. READ MORE

  7. 5. On the neuropeptide mRNA expression following neuropsychopharmacological treatments

    Author : Olof Zachrisson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Cholecystokinin; Excitotoxicity; Electroconvulsive; In situ hybridisation; Kainic acid; Lithium; Manic-depressive illness; Neuropeptide Y; Rat brain; Schizophrenia; Seizure; Somatostatin; Substance P; Tachykinin receptor;

    Abstract : In addition to classical neurotransmitters, an increasing number of neuropeptides have been found in the brain. Although neuropeptides may play important roles especially in higher brain functions such as emotion, mood, memory, and learning, most focus has been directed upon classical neurotransmitters and their receptors. READ MORE