Search for dissertations about: "Cecilia Williams"

Found 5 swedish dissertations containing the words Cecilia Williams.

  1. 1. Molecular archaeology of cancer

    Author : Cecilia Williams; KTH; []
    Keywords : ;

    Abstract : Alterations of the p53 tumor suppressor gene plays animportant role in the development of many types of cancers.This and the suggestion that the presence or absence of p53mutations might have both prognostic and therapeuticconsequences, imply the importance of reliable techniques forp53 sequence determination. READ MORE

  2. 2. Role and mechanism of estrogen receptor beta in the ovary and colon

    Author : Madeleine Birgersson; Cecilia Williams; Amena Archer; Claudia Kutter; Eduardo Villablanca; David Moore; KTH; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicinsk teknologi; Medical Technology;

    Abstract : Estrogen regulates a variety of important physiological functions in both males and females, where the regulation of female reproduction and the development of sexual organs are typical examples. The effects of estrogen are predominantly exerted via signaling through the two nuclear receptors estrogen receptor α (ERα) and β (ERβ), or the membrane G protein-coupled estrogen receptor 1 (GPER1). READ MORE

  3. 3. Estrogen signaling in colon inflammation and colorectal cancer

    Author : Linnea Hases; Cecilia Williams; Joëlle Rüegg; KTH; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medical Technology; Medicinsk teknologi;

    Abstract : Colorectal cancer (CRC) is the third most deadly form of cancer in the Western world. Although screening efforts have reduced the overall mortality, the incidence is increasing among young adults. READ MORE

  4. 4. Estrogen receptor beta transcriptional regulation: A potential mechanism for colon cancer prevention

    Author : Rajitha Indukuri; Cecilia Williams; Jason Carroll; KTH; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medical Technology; Medicinsk teknologi;

    Abstract : Colorectal cancer (CRC) is the third leading cause of death from cancer in both men andwomen in the Western world. Improved screening efforts, surveillance, and treatment havereduced CRC mortality in older patients. However, the incidence is increasing in young adults,even in the absence of CRC family history. READ MORE

  5. 5. Antibody-based subcellular localization of the human proteome

    Author : Marie Skogs; Emma Lundberg; Hans Blom; Cecilia Williams; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Human proteome; Subcellular localization; Organelles; Immunofluorescence; Fixation; Permeabilization; Antibody validation; Bioteknologi; Biotechnology;

    Abstract : This thesis describes the use of antibodies and immunofluorescence for subcellular localization of proteins. The key objective is the creation of an open-source atlas with information on the subcellular location of every human protein. READ MORE