Search for dissertations about: "Cell Cycle drug effects"
Showing result 1 - 5 of 51 swedish dissertations containing the words Cell Cycle drug effects.
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1. Effects of polyamine pool manipulation on genes expressed during the cell cycle
Abstract : The polyamines - putrescine, spermidine and spermine - are polycations found within cells. They have been shown to be essential for optimal cell proliferation and cell survival. Cells maintain their polyamine levels in a well-regulated system involving biosynthesis, catabolism and uptake/excretion. READ MORE
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2. Visualizing Interacting Biomolecules In Situ
Abstract : Intra- and intercellular information is communicated by posttranslational modifications (PTMs) and protein-protein interactions, transducing information over cell membranes and to the nucleus. A cells capability to respond to stimuli by several highly complex and dynamic signaling networks provides the basis for rapid responses and is fundamental for the cellular collaborations required in a multicellular organism. READ MORE
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3. Preclinical investigation of novel therapies against neuroblastoma
Abstract : Neuroblastoma is a childhood tumor of the sympathetic nervous system and the most common tumor form diagnosed in infants. Patients with aggressive tumors are treated intensely with multi-modal therapy including chemotherapy, surgery, radiotherapy and immunotherapy. READ MORE
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4. Cancer and Inflammation : Role of Macrophages and Monocytes
Abstract : Macrophages are cells of the innate immune system that can be found in large quantities in cancer tumors and affect cancer progression by regulating growth and invasiveness of cancer cells. There are two main phenotypes of macrophages denoted M1 and M2. READ MORE
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5. The Regulation of Growth and Survival in Human Multiple Myeloma Cells by IGF-I Receptor Signaling
Abstract : Multiple myeloma (MM) is an incurable B-cell malignancy mainly localized to the bone marrow. Our aim was to examine the growth- and survival-promoting role of the IGF-IR and its downstream signaling components in MM cells to identify potential targets for therapy. READ MORE