Search for dissertations about: "Cell culture scaffold"
Showing result 1 - 5 of 32 swedish dissertations containing the words Cell culture scaffold.
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1. Pancreatic extracellular communication. Applications to beta cell cultures and islet amyloid polypeptide aggregation
Abstract : Diabetes mellitus (DM) is a disease with epidemic proportions due to increased incidences worldwide, persistence of undiagnosed cases, uncontrolled forms of the disease, association with cardiovascular complications, and lack of definitive treatment options. In particular, type 2 DM (T2DM) is placing an enormous financial burden on worldwide healthcare systems that will increase in the futureThere is a need to develop physiological assay platforms that provide functionally relevant models of diabetes in order to accelerate the discovery of new treatments. READ MORE
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2. Development and optimization of a 3D in vitro model for osteogenic biomaterial evaluation
Abstract : Despite the innate regenerative capabilities of bone tissue, self-repair is impaired when an injury exceeds the critical size threshold because of trauma, congenital, or pathological conditions. Autologous transplantation is the gold standard to reconstruct large bone defects. READ MORE
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3. Integration of Electrospun Materials in Microelectronic and Biomedical Applications
Abstract : This thesis demonstrates the use of electrospinning and the novel properties of electrospunmaterials in two fields.The microelectronics industry has identified thermal interface materials as one of themajor bottlenecks hindering further integration at packaging level. READ MORE
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4. Studies on various culture systems for chondrocytes and osteoblasts
Abstract : Osteoarthritis and osteochondral defects are ailments that are increasing in frequency as the lifespan of the population increases and sedentary lifestyle becomes more common. Osteoarthritis is an inflammatory disease that causes the progressive degeneration of articular surfaces and the underlying bone. READ MORE
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5. Heparan Sulfate in the Amyloidosis and Inflammation of Alzheimer’s Disease
Abstract : Alzheimer’s disease (AD) is a neurodegenerative disorder, with extensive evidence implicating the misfolding, aggregation and deposition of the amyloid-β (Aβ) peptide as central to the pathogenesis. Heparan sulfate (HS) is an interactive glycosaminoglycan, attached to core proteins as HS proteoglycans (HSPGs). READ MORE