Search for dissertations about: "Cell factories"

Showing result 1 - 5 of 24 swedish dissertations containing the words Cell factories.

  1. 1. Droplet microfluidics for single cell and nucleic acid analysis

    University dissertation from Stockholm : KTH Royal Institute of Technology

    Author : Prem Kumar Periyannan Rajeswari; KTH.; [2016]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Acoustophoresis; Biomarker detection; Cell behavior analysis; Cell factories; Droplet microfluidics; Droplet PCR; High throughput biology; Label-free enrichment; Single cell analysis; Biotechnology; Bioteknologi;

    Abstract : Droplet microfluidics is an emerging technology for analysis of single cells and biomolecules at high throughput. The controlled encapsulation of particles along with the surrounding microenvironment in discrete droplets, which acts as miniaturized reaction vessels, allows millions of particles to be screened in parallel. READ MORE

  2. 2. Towards membrane engineering as a tool in cell factory design: A case study on acetic acid tolerance in Saccharomyces cerevisiae

    University dissertation from ; Chalmers tekniska högskola; Gothenburg

    Author : Lina Lindahl; [2017]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; butanol; inhibitors; lipidomics; Key words: Lignocellulose; Zygosaccharomyces bailii; molecular dynamics simulations; membrane permeability; carbon-14 uptake; ethanol; robustness;

    Abstract : The sustainable production of fuels, chemicals, and materials using renewable resources is a necessity if we are to reduce our ecological footprint and the rate of climate change. Lignocellulosic biomass, the major constituent of plant cell walls, is a renewable raw material with great potential due to its high abundance. READ MORE

  3. 3. Engineering microbial cell factories for protein production

    University dissertation from Stockholm : Department of Biochemistry and Biophysics, Stockholm University

    Author : Kiavash Mirzadeh; Stockholms universitet.; [2018]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Protein production; expression vector; recombinant DNA; Translation initiation region; Escherichia coli; mRNA secondary structure; Synthetic evolution; biokemi; Biochemistry;

    Abstract : Proteins are often produced using microbial cell factories for academic or industrial purposes. Protein production is however not an open-and-shut procedure. Production yields often vary in an unpredictable and context dependent manner, limiting the rational design of a straightforward production experiment. READ MORE

  4. 4. Systems Biology of the Secondary Metabolism in Filamentous Fungi

    University dissertation from ; Chalmers tekniska högskola; Gothenburg

    Author : Jens Christian Froslev Nielsen; [2018]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; genomics; systems biology; secondary metabolites; antibiotics; Next-generation sequencing; secondary metabolism; filamentous fungi; cell factories; Penicillium;

    Abstract : Filamentous fungi constitute a rich reservoir of pharmaceutically relevant bioactive small molecules. These compounds, commonly referred to as secondary metabolites, are widely used as antibiotics for the treatment of microbial infections, but also as other pharmaceuticals such as immunosuppressors, cholesterol lowering agents and anticancer drugs. READ MORE

  5. 5. SYSBIOMICS of Aspergilli: SYStems Biology, BIoinformatics and OMICS analysis of Aspergilli cell factories

    University dissertation from ; Chalmers tekniska högskola; Gothenburg

    Author : Wanwipa Vongsangnak; [2009]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Systems Biology; Aspergilli; Bioinformatics; Omics analysis;

    Abstract : Aspergilli represent a group of filamentous fungi that plays a key role in industrialbiotechnology, and as human, animal and plant pathogens. Here three Aspergillus species,namely Aspergillus oryzae, Aspergillus niger and Aspergillus nidulans are considered. READ MORE