Search for dissertations about: "Cell factories"

Showing result 6 - 10 of 52 swedish dissertations containing the words Cell factories.

  2. 6. Engineering microbial cell factories for protein production

    Author : Kiavash Mirzadeh; Daniel Daley; Grzegorz Kudla; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Protein production; expression vector; recombinant DNA; Translation initiation region; Escherichia coli; mRNA secondary structure; Synthetic evolution; Biochemistry; biokemi;

    Abstract : Proteins are often produced using microbial cell factories for academic or industrial purposes. Protein production is however not an open-and-shut procedure. Production yields often vary in an unpredictable and context dependent manner, limiting the rational design of a straightforward production experiment. READ MORE

  4. 7. A holistic view on transcriptional regulatory networks in S. cerevisiae: Implications and utilization

    Author : David Bergenholm; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Transcription factors; S. cerevisiae; chemostat; transcriptomics; regulatory networks;

    Abstract : Life; perhaps it is bold to start an abstract with this powerful word, but this is where I will start. My research is at the heart of life. READ MORE

  5. 8. Systems Biology of the Secondary Metabolism in Filamentous Fungi

    Author : Jens Christian Froslev Nielsen; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; genomics; systems biology; secondary metabolites; antibiotics; Next-generation sequencing; secondary metabolism; filamentous fungi; cell factories; Penicillium;

    Abstract : Filamentous fungi constitute a rich reservoir of pharmaceutically relevant bioactive small molecules. These compounds, commonly referred to as secondary metabolites, are widely used as antibiotics for the treatment of microbial infections, but also as other pharmaceuticals such as immunosuppressors, cholesterol lowering agents and anticancer drugs. READ MORE

  6. 9. Towards sustainable plastics : Microbial production of aromatic and aliphatic building blocks from biobased feedstock and plastic hydrolysate

    Author : Oliver Englund Örn; Bioteknik; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Cell factories; Biobased plastics; Protocatechuic acid; Adipic acid; 4-Hydroxybyratate; 1; 4-Butanediol; PBAT; Enzymatic recycling; Synthetic promoter library;

    Abstract : The current plastic system is unsustainable and needs to change. Plastics are mainly produced from fossil feedstock, contributing to greenhouse gas emissions, and low rate of post-consumer recycling results in pollution on land and in oceans with high ecological impact, and huge loss of valuable material. READ MORE

  7. 10. Understanding and improving microbial cell factories through Large Scale Data-approaches

    Author : Daniel Brink; Teknisk mikrobiologi; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Microbiology; lignocellulose; lignin; D-xylose; Saccharomyces cerevisiae; Pseudomonas putida; bioinformatics; genome assembly; flow cytometry; metabolic engineering; sugar sensing signalling;

    Abstract : Since the advent of high-throughput genome sequencing methods in the mid-2000s, molecular biology has rapidly transitioned towards data-intensive science. Recent technological developments have increased the accessibility of omics experiments by decreasing the cost, while the concurrent design of new algorithms have improved the computational work-flow needed to analyse the large datasets generated. READ MORE