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Showing result 1 - 5 of 20 swedish dissertations matching the above criteria.

  1. 1. Intrinsically Disordered Domains of the B Cell Receptor Cell-Free Expression and Characterization by NMR

    Author : Linnéa Isaksson; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Naturvetenskap;

    Abstract : After the last twenty years of research, the occurrence of flexible proteins without a fixed three-dimensional structure are no longer considered to be rare exceptions from the structure-function paradigm. Instead, intrinsically disordered proteins (IDPs) have become one of the most interesting subjects of modern protein research. READ MORE

  2. 2. Isotope labeling of proteins for spectroscopic studies

    Author : Emil Gustavsson; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Isotope labeling; Proteins; Cell-free protein expression; NMR; IR; Infrared;

    Abstract : Protein structural dynamics have been closely tied to the molecular mechanisms controlling for example enzyme activities. In my work, I have mainly studied the bacteriophytochrome from Deinococcus radiodurans. READ MORE

  3. 3. Engineering of Human Fetal Hemoglobin

    Author : Karin Kettisen; Tillämpad biokemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; fetal hemoglobin; protein engineering; recombinant protein production; protein purification; chromatography; oxygen carrier; redox reactions; net surface charge; DNA cleavage;

    Abstract : In blood, the oxygen-transporting protein hemoglobin (Hb) governs the oxygenation of cells and tissues. Naturally, this protein has claimed a place in the center of the research field of artificial oxygen therapeutics. READ MORE

  4. 4. Structural analyses of immune cell receptor signalling and activation

    Author : Maria Saline; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; structural biology; NMR; protein-protein interaction; immunology;

    Abstract : Structural biology is a scientific field where the aim is to observe macromolecules on a atomic level to understand their functions. Often these macromolecules are proteins that make, almost, everything happen within the cells; from hormones and enzymes to building blocks and controlling gene expression. READ MORE

  5. 5. Bronchoalveolar lavage and serum protein patterns in healthy individuals and sarcoidosis patients : a proteomics approach

    Author : Fariba Sabounchi Schütt; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Sarcoidosis; BALF; serum; proteomics; 2-D electrophoresis; protein-spot pattern; protein identification;

    Abstract : The etiology of sarcoidosis remains unknown. Although biochemical changes are frequently observed in sarcoidosis, the problem of finding distinct biomarkers remains. Only a few markers are defined in this disease. READ MORE