Search for dissertations about: "Cell-penetrating peptides"
Showing result 11 - 15 of 73 swedish dissertations containing the words Cell-penetrating peptides.
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11. Oligonucleotide Complexes with Cell-Penetrating Peptides : Structure, Binding, Translocation and Flux in Lipid Membranes
Abstract : The ability of cell-penetrating peptides to cross plasma membranes has been explored for various applications, including the delivery of bioactive molecules to inhibit disease-causing cellular processes. The uptake mechanisms by which cell-penetrating peptides enter cells depend on the conditions, such as the cell line the concentration and the temperature. READ MORE
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12. Cell-penetrating peptides and bioactive cargoes : Strategies and mechanisms
Abstract : The cell membrane is an impermeable barrier for most macromolecules. Recently discovered cell-penetrating peptides (CPPs) have gained lot of attention because they can cross the membrane, and even more, carry cargoes with them. How CPPs enter cells is still not clear, while the delivery of different cargoes has been convincingly shown. READ MORE
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13. Cell-penetrating peptide targeting mitochondria : Design, synthesis, characterization, and biological effects
Abstract : More than twenty years after the discovery of the first cell-penetrating peptide (CPP), a large number of both naturally occurring as well as engineered CPPs have been discovered. Generally, CPPs are short polycationic sequences of less than 30 amino acids that are able to translocate different cargoes into cells. READ MORE
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14. PepFect14, a Versatile Cell-Penetrating Peptide
Abstract : Cell-penetrating peptides have been discovered almost three decades ago and there are, nowadays, thousands of available sequences. They offer multiple applications in the field of drug delivery as they are able to carry therapeutic macromolecules across the plasma membrane. READ MORE
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15. Complexes of cell-penetrating peptides with oligonucleotides : Structure, binding and translocation in lipid membranes
Abstract : The fundamental element of life known to man is the gene. The information contained in genes regulates all cellular functions, in health and disease. The ability to selectively alter genes or their transcript intermediates with designed molecular tools, as synthetic oligonucleotides, represents a paradigm shift in human medicine. READ MORE
