Search for dissertations about: "Cell-penetrating peptides"
Showing result 16 - 20 of 73 swedish dissertations containing the words Cell-penetrating peptides.
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16. Acylated cell-penetrating peptides for nucleic acid delivery
Abstract : In recent decades many new methods have been developed to cure or treat genetical disorders such as cancer, viral infections or inheritable diseases. The problem is that the nucleic acids and their synthetic analogs, oligonucleotides, are not able to cross the cell membrane due to their physicochemical properties like high negative charge and size. READ MORE
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17. Structures, toxicity and internalization of cell-penetrating peptides
Abstract : Cellular internalization is a highly regulated process controlled by proteins in the plasma membrane. Large and hydrophilic compounds, in particular, face difficulties conquering the plasma membrane barrier in order to gain access to intracellular environment. This puts serious constrains on the drug industry since many drugs are hydrophilic. READ MORE
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18. Cell-penetrating peptides in cargo delivery : In vitro studies on uptake and in vivo studies on tumor targeting
Abstract : The capability of cell-penetrating peptides (CPPs) to transport cargos over different cellular membranes both in vitro and in vivo have drawn major attention in the past decade. Three main topics on the application of CPPs have been studied in this thesis. READ MORE
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19. Cell-penetrating peptide based nanocomplexes for oligonucleotide delivery
Abstract : Oligonucleotide-based drugs hold great promise for the treatment of many types of diseases, ranging from genetic disorders to viral infections and cancer. The problem is that efficient delivery across the cell membrane is required for oligonucleotides to have their desired effect. Cell-penetrating peptides (CPPs) provide a solution to this problem. READ MORE
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20. Cell-penetrating peptides and oligonucleotide delivery
Abstract : .... READ MORE