Search for dissertations about: "Central Nervous System : pathology"

Showing result 1 - 5 of 57 swedish dissertations containing the words Central Nervous System : pathology.

  2. 1. Investigating the function of Anaplastic Lymphoma Kinase

    Author : Emma Vernersson Lindahl; Bengt Hallberg; Ruth Palmer; Göran Roos; Carina Hellberg; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ALK; nervous system; knockout; development; Jelly-Belly; Pathology; Patologi;

    Abstract : Anaplastic Lymphoma Kinase (ALK) was discovered in 1994, as a chromosomal translocation, t(2;5)(p23;q35), often seen in Anaplastic Large Cell Lymphomas (ALCL). Since then ALK has been extensively studied in this disease as well as in different model organisms. READ MORE

  4. 2. The vestibular system, a tool to study neurotoxicants in the central nervous system

    Author : Magnus Niklasson; Måns Magnusson; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : The vestibular and opto-ocular motor (VOOM) system in pigmented rats was investigated. Horizontal eye movements were recorded by the magnetic search coil technique during different kind of stimulations. The dynamics of the vestibular ocular reflex (VOR) and the optokinetic reflex (OKR) as well as the interaction of the two rel1exes were analysed. READ MORE

  5. 3. Immune regulation within the central nervous system and its role in demyelinating diseases

    Author : Bao-Guo Xiao; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Multiple sclerosis (MS) and its animal model, experimental allergic encephalomyelitis (EAE), are diseases of the central nervous system (CNS) characterized by perivascular mononuclear inflammation and oligodendrocyte loss with demyelination. However, it is still not clear whether the pathology in MS and EAE is due to neuroantigen-specific CD4+ T cell-mediated autoimmune responses and/or bystander myelin damage resulting from an inflammatory response. READ MORE

  6. 4. Of mice and men : SOD1 associated human amyotrophic lateral sclerosis and transgenic mouse models

    Author : Karin Sixtensdotter Graffmo; Thomas Brännström; Stefan Marklund; Elisabeth Englund; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; aggregates; ALS; amyotrophic lateral sclerosis; inclusions; misfolded; vacuolisation; SOD1; transgenic; Pathology; Patologi;

    Abstract : Amyotrophic lateral sclerosis, ALS, is a progressive fatal neurodegenerative disorder affecting motor neurones in motor cortex, brain stem and spinal cord. This inevitably leads to paralysis, respiratory failure and death. READ MORE

  7. 5. Cerebrum Illuminans : Mass Spectrometric Analysis of Protein and Peptide Dynamics in Neurological Diseases

    Author : Jörg Hanrieder; Jonas Bergquist; Malin Andersson; Ulf Hellman; Alma Burlingame; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; mass spectrometry; central nervous system; neurological disease; proteomics; MALDI imaging; Analytical chemistry; Analytisk kemi; Kemi med inriktning mot analytisk kemi; Chemistry with specialization in Analytical Chemistry;

    Abstract : The human brain (lat. cerebrum) is the most complex and heterogeneous organ in the human body. It is involved in a great number of body functions like movement, touch sensing, vision, hearing, smelling, hormone regulation and many more. In no other organ, the molecular communication mechanisms between different cells are so poorly understood. READ MORE