Search for dissertations about: "Ceramide"

Showing result 21 - 25 of 36 swedish dissertations containing the word Ceramide.

  2. 21. The advantages of being small : Glycosyltransferases in many dimensions and glycolipid synthesis in Mycoplasma Pneumoniae

    Author : Maria Rosén Klement; Åke Wieslander; Christelle Breton; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Glycosyltransferase; lipid; membrane; glycolipid; ACC; PLS-DA; Biochemistry; Biokemi; biokemi; Biochemistry;

    Abstract : The synthesis and breakdown of sugars is one of the most important functions in Nature. Consequently, sugar structures are used both as energy storage and as building blocks to stabilise and protect the cell. The formation of these structures is performed by glycosyltransferases (GT), an enzyme group structurally conserved within all kingdoms. READ MORE

  4. 22. Cannabinoids as modulators of cancer cell viability, neuronal differentiation, and embryonal development

    Author : Sofia Gustafsson; Stig Jacobsson; Birgitta Sander; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cannabinoids; cell viability; neuronal differentiation; colorectal cancer; chick embryo; biokemisk farmakologi; biochemical pharmacology; Toxicology; toxikologi;

    Abstract : Cannabinoids (CBs) are compounds that activate the CB1 and CB2 receptors. CB receptors mediate many different physiological functions, and cannabinoids have been reported to decrease tumor cell viability, proliferation, migration, as well as to modulate metastasis. READ MORE

  5. 23. Influence of host genetics on innate immunity and susceptibility to urinary tract infection

    Author : Bryndis Ragnarsdottir; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neutrophils; IRF3; Innate Immunity; urinary tract infections; acute pyelonephritis; asymptomatic bacteriuria; Toll-like receptor 4; CXCR1; TLR4 adaptors; polymorphisms;

    Abstract : It has been known for a long time that the clinical manifestations of urinary tract infections (UTI) differ markedly between individuals, ranging from a sometimes beneficial, asymptomatic state to life threatening infections. This variability in clinical manifestation can be explained in part by the arsenal of virulence factors of the bacteria but the predisposition of the patient is equally important. READ MORE

  6. 24. Responding Model Membranes. Lipid Phase Behaviour, Domain Formation and Permeability

    Author : Emma Sparr; Fysikalisk kemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Water and solute flux; Gradients; Monolayer; Two-dimensional crystals; Line activiy; Osmotic stress; Interlamellar forces; Phospholipid-cholesterol interactions; Phase transitions; Bilayer stack; Stratum corneum; Physical chemistry; Fysikalisk kemi;

    Abstract : This thesis concerns the interplay between the lipid phase behaviour, domain formation and the permeability of bilayer membranes. An essential part of this work has been the understanding of the phase transitions and equilibrium properties of lipid bilayers. READ MORE

  7. 25. Characterizing and exploiting the endocytic pathway for macromulecular delivery

    Author : Jeremy Bost; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Macromolecular drugs with cytosolic or nuclear targets often exhibit low therapeutic activity due, at least in part, to their inability to escape endosomal compartments following cellular internalization. There exist a range of strategies to address this inefficient delivery by attempting to bolster the endosomal escape of the therapeutic cargo. READ MORE