Search for dissertations about: "Cervical intraepithelial neoplasia"

Showing result 6 - 10 of 32 swedish dissertations containing the words Cervical intraepithelial neoplasia.

2. 6. Cervical intraepithelial neoplasia in migrant women living with HIV

   Author : Christina Carlander; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The aim of this thesis was to study high-grade cervical intraepithelial neoplasia (CIN) in women living with HIV (WLWH) in Sweden compared with HIV-negative women (HNW) of the same region of birth. In Paper I we assessed the cumulative incidence (CuI) and hazard ratio (HR) of CIN3, adenocarcinoma, and invasive cervical cancer (CIN3+) in a cohort of WLWH (n = 893) and HNW (n = 205 842) by linking the Swedish national HIV registry (InfCare HIV) with the Swedish Population Registry (SPR) and the Swedish National Cervical Screening Registry (NKCx). READ MORE

4. 7. Tissue tumor marker expression in normal cervical tissue and in cervical intraepithelial neoplasia, for women who are at high risk of human papilloma virus infection, are smokers, contraceptive users or in fertile age

   Author : Raghad Samir; Dan Hellberg; Anna Asplund; Pär Sparen; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tumor markers; cervical intraepithelial neoplasia; smoking; contraceptive use; sex steroid hormones; HPV infection; Obstetrik och gynekologi; Obstetrics and Gynaecology;

   Abstract : The aim of this research was to study the correlation between tissue tumor marker expression and HR-HPV infection, smoking, hormonal contraceptive use and sex steroids in women with cervical intraepithelial neoplasia or normal epithelium. The study investigated the expression of 11 tumor markers in cervical biopsies obtained from 228 women with different diagnoses ranging from normal cervical epithelium to various stages of CIN. READ MORE

5. 8. Molecular Pathogenesis of Cervical Carcinoma : Analysis of Clonality, HPV16 Sequence Variations and Loss of Heterozygosity

   Author : Xinrong Hu; Björn Hagmar; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; cervical carcinoma; CIN; HPV; LOH; X-chromosome inactivation; clonality; molecular pathogenesis; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

   Abstract : A previous model of morphological pathogenesis assumed that cervical carcinoma is of monoclonal origin and progresses through multiple steps from normal epithelium via CINS into invasive carcinomas. The aim of this study was to investigate the molecular mechanism of pathogenesis of cervical neoplasia. READ MORE

6. 9. Detection of human papillomavirus : a study of normal cells, cervical intraepithelial neoplasia and cancer of the uterine cervix

   Author : Magnus Evander; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HPV; PCR; General primers; Genital cancer;

   Abstract : Human papillomavirus (HPV) infections of the genital tract are now recognized to be among the most prevalent sexually transmitted diseases and also a contributing factor to some cancers of the lower genital tract of women and men. Presence of HPV in a clinical specimen is confined to detection of the HPV genome by DNA hybridization techniques. READ MORE

7. 10. HPV genotyping and potential progression markers in cervical intraepithelial neoplasia : clinical and diagnostic impact

   Author : Sophia Brismar Wendel; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The aim of this thesis is to identify clinically useful early molecular markers to predict progression to carcinoma in women with preinvasive lesions of the cervix, for the purpose of improving care of these women and enabling more individualized treatment. In order to define the human papillomavirus (HPV) types in minor cytological abnormalities, 343 liquid-based cytology (LBC) samples with atypical squamous cells of uncertain significance (ASCUS) and with low-grade squamous intraepithelial lesions (LSIL) were genotyped using Linear Array. READ MORE