Search for dissertations about: "Charles G. Mullighan"

Found 1 swedish dissertation containing the words Charles G. Mullighan.

2. 1. Molecular mechanisms in lymphoid restriction : securing the B lineage fate

   Author : Josefine Åhsberg; Mikael Sigvardsson; Jan-Ingvar Jönsson; Charles G. Mullighan; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Abstract : With the work in this thesis I have aimed to deepen the understanding of the mechanisms behind the development of different blood cell lineages with a specific focus on B cell development.To understand the interplay between extracellular signaling and transcription factor networks in early lymphoid development we investigated the functional collaborations of FLT3 and IL7R. READ MORE