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Showing result 1 - 5 of 19 swedish dissertations matching the above criteria.

  2. 1. Aggressive lymphoma

    Author : Mats Jerkeman; Bröstcancer-genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cytology; BCL6 rearr; 1q21-23; cytogenetics; histopathology; P-glycoprotein; p53; BCL2; Ki-67; immunohistochemistry; proliferation; dose intensity; health-related quality of life; International Prognostic Index; prognostic factors; aggressive lymphoma; chemotherapy; patologisk anatomi; Patologi allmän ; pathological anatomy; General pathology; cancer; onkologi; Cytologi; cancerology; oncology;

    Abstract : Aggressive lymphoma is a rapidly growing tumour of lymphocyte origin, potentially curable with chemotherapy. In a trial by the Nordic Lymphoma Group, 405 patients with aggressive lymphoma were included, and randomised to receive either the standard chemotherapy regimen, CHOP, or a weekly multidrug regimen, MACOP-B. READ MORE

  4. 2. Towards improved oncological treatment of esophageal and gastric cancer. Clinical and translational studies

    Author : David Borg; Tumörmikromiljö; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Esophageal adenocarcinoma; Gastric cancer; PODXL; Prognosis; Prediction; Chemotherapy dose intensity; Dysphagia; Radiotherapy;

    Abstract : BackgroundThe overall aim of this thesis was to improve the oncological treatment strategies in esophageal and gastric adenocarcinoma (EGAC). Podocalyxin-like protein 1 (PODXL) has been associated with poor prognosis in other cancers and we wanted to investigate its potential role as a prognostic and predictive biomarker in resectable EGAC. READ MORE

  5. 3. Nausea and emesis in cancer chemotherapy : aspects of occurrence, assessment and treatment

    Author : Sussanne Börjeson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Cancer chemotherapy; cancer nursing; nausea; emesis; antiemetics; well-being;

    Abstract : Nausea and emesis are two of the most distressing side-effects cancer patients may experience during chemotherapy. The general aim of this thesis was to acquire knowledge to be used for improving the care of cancer patients during chemotherapy, in particular for the prevention and palliation of chemotherapy-induced nausea and emesis. READ MORE

  6. 4. Predictive and prognostic factors in cervical carcinomas treated with (chemo-) radiotherapy

    Author : Louise Bohr Mordhorst; Bengt Sorbe; Preben Kjölhede; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cervical carcinoma; radio-chemotherapy; biomarkers; predictive factors; prognostic factors; multiprotein analysis; Hedgehog pathway; Wnt β-catenin pathway; Surgery; Kirurgi;

    Abstract : A series of 131 women with cervical carcinoma FIGO stage I-IV were treated with external radiotherapy and intracavitary brachytherapy. In 47 patients (36%) concomitant chemotherapy was given. One hundred and twenty-one tumors (92%) achieved complete remission. Addition of chemotherapy increased primary cure rate to 98%. READ MORE

  7. 5. Treatment Planning of High Dose-Rate Brachytherapy - Mathematical Modelling and Optimization

    Author : Björn Morén; Torbjörn Larsson; Åsa Carlsson Tedgren; Bram Gorissen; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Cancer is a widespread class of diseases that each year affects millions of people. It is mostly treated with chemotherapy, surgery, radiation therapy, or combinations thereof. High doserate (HDR) brachytherapy (BT) is one modality of radiation therapy, which is used to treat for example prostate cancer and gynecologic cancer. In BT, catheters (i. READ MORE