Search for dissertations about: "Chiral Stationary Phase"

Showing result 1 - 5 of 9 swedish dissertations containing the words Chiral Stationary Phase.

  1. 1. Aspects of Porous Graphitic Carbon as Packing Material in Capillary Liquid Chromatography

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Anna Törnkvist; Wolfgang Lindner; [2003]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Analytical chemistry; PGC; porous graphitic carbon; stationary phase; packing material; LC; liquid chromatography; miniaturized; chiral; enantiomer; ESI; electrospray ionization; mass spectrometry; polar compounds; L-DOPA; dopamine; biological samples; biological matrix; Analytisk kemi; PGC; poröst grafitiserat kol; stationärfas; packningsmaterial; LC; vätskekromatografi; miniatyriserade system; kiral; enantiomer; ESI; electrospray jonisation; mass spektrometri; polära föreningar; L-DOPA; dopmamine; biologiska prover; biologisk matris; NATURAL SCIENCES Chemistry Analytical chemistry; NATURVETENSKAP Kemi Analytisk kemi; Analytical Chemistry; Analytisk kemi;

    Abstract : In this thesis, porous graphitic carbon (PGC) has been used as packing material in packed capillary liquid chromatography. The unique chromatographic properties of PGC has been studied in some detail and applied to different analytical challenges using both electrospray ionization-mass spectrometry (ESI-MS) and ultra violet (UV) absorbance detection. READ MORE

  2. 2. Molecular Imprinting Technology. Design and Recognition Properties of Antibody/Receptor Mimics

    University dissertation from Pure and Applied Biochemistry, Lund University

    Author : Olof Ramström; [1996]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Template Polymerisatio; Steroid; Receptor; Racemic Resolution; Polymer; Molecular Recognition; Molecular Imprinting; Enantiomeric Separation; de novo Design; Chromatography; Chiral Stationary Phase; Chiral Recognition; Biorecognition; Antibody; Biomimetic; Biochemistry; Metabolism; Biokemi; metabolism; Biotechnology; Bioteknik;

    Abstract : Molecular imprinting technology is derived from the concept of creating designed recognition sites in macromolecular matrices by means of template polymerisation. Molecularly imprinted polymers are able to mimic recognition in natural binding events, such as antibody-antigen and receptor-ligand interactions. READ MORE

  3. 3. New Techniques for Chiral Separations

    University dissertation from Karlstad : Karlstads universitet

    Author : Jeanette Olsson; Lars Blomberg; Steen Honoré Hansen; [2008]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; analytical chemistry; chiral separation; GC; CE; CEC; NATURAL SCIENCES Chemistry Analytical chemistry; NATURVETENSKAP Kemi Analytisk kemi; Kemi; Chemistry;

    Abstract : Gas chromatography (GC) has been utilized for the study of enantiomer resolution of the atropisomers of PCBs, o,p´-DDD and o,p´-DDT. Different substituents and concentrations of cyclodextrin, capillary dimensions and type of stationary phase films have been investigated to achieve the resolution of as many of the atropisomers on one column as possible. READ MORE

  4. 4. Enantioseparation of drugs and related compounds using chiral mobile phase additives

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Ngoc Hang Huynh; [1998]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; Farmaceutisk kemi; PHARMACY Pharmaceutical chemistry; FARMACI Farmaceutisk kemi; analytisk farmaceutisk kemi; Analytical Pharmaceutical Chemistry;

    Abstract : Neutral and anionic chiral mobile phase additives have been employed to separate enantiomers of drugs and related compounds using aqueous buffer solution and hydro-organic solvent mixtures as mobile phases.Ester derivatives of tartaric acid, e. g. READ MORE

  5. 5. Development of LC-MS/MS Methods for the Analysis of Chiral and Achiral Pharmaceuticals and Metabolites in Aqueous Environmental Matrices

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Victoria K.H. Barclay; Curt Pettersson; Monika Johansson; Niklas Tyrefors; Mohamed Abdel-Rehim; [2012]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Environmental water matrices; chiral separation; LC-MS MS; trace analysis; method development; active pharmaceutical ingredients; metabolites; Analytical Pharmaceutical Chemistry; Analytisk farmaceutisk kemi;

    Abstract : This thesis describes the development of liquid chromatography tandem mass spectrometry (LC-MS/MS) methods for the trace analysis of active pharmaceutical ingredients (APIs) and their metabolites in aqueous environmental matrices. The research was focused on the development of chiral LC-MS/MS methods for the analysis of fluoxetine and metoprolol, as well as their chiral metabolites in environmental water samples. READ MORE