Search for dissertations about: "Cholecystokinin"

Showing result 1 - 5 of 62 swedish dissertations containing the word Cholecystokinin.

  1. 1. On Cholecystokinin and Phospholipase A2 in Insulin Secretion - an Experimental Study With Reference to the Development of Diabetes

    Author : Erik Simonsson; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 2 Diabetes; Insulin Resistance; Islet; Beta-cell; Insulin Secretion; Ca2 -Dependency; Intracellular Signalling; Phospholipase A2; Cholecystokinin; Non-glucose Secretagogues; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

    Abstract : In view of unsolved issues regarding cellular events underlying the adaptation of insulin secretion to insulin resistance, together with the observation that insulin secretion induced by the gastrointestinal hormone and neuropeptide cholecystokinin (CCK) is not solely explained by phospholipase C-protein kinase C (PLC-PKC) pathway activation, this study aimed at delineate mechanisms responsible for the hyperinsulinemia in insulin resistance, with particular attention paid to the action of glucose vs. non-glucose secretagogues, such as CCK. READ MORE

  2. 2. The cholecystokinin receptor family : molecular cloning and pharmacological characterization

    Author : Isabelle Nilsson; Dan Larhammar; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Cholecystokinin (CCK) and gastrin are hormones/neurotransmittors of the gastrointestinal tract and central nervous system. The receptors for gastrin and CCK are members of the G protein-coupled receptor family. The aim of this study was to clone and pharmacologically characterize vertebrate and invertebrate CCK receptors and splice variants. READ MORE

  3. 3. Secretory and anti-inflammatory actions of some gastro-intestinal hormones in salivary glands

    Author : Hülya Çevik Aras; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : salivary glands; protein secretion; synthesis; inflammation; β-defensins; myeloperoxidase; cholecystokinin; gastrin; melatonin; nitric oxide; nerve stimulation;

    Abstract : Textbooks generally state that the secretory activity of salivary glands is solely regulated by nerves. This view is challenged in the present Thesis, using the parotid gland of the anaesthetized rat as experimental in vivo model. READ MORE

  4. 4. Liver regeneration : With reference to malnutrition and growth factors

    Author : Stefan Skullman; Linköpings universitet; []
    Keywords : cholecystokinin; energy substrates; epidermal growth factor; insulin-like growth factor I; liver composition; liver regeneration; malnutrition; pancreaticobiliary diversion; protein synthesis; rat; transfonning growth factor alpha; MEDICINE; MEDICIN;

    Abstract : The liver has a unique capacity to regenerate after damage, irrespective of cause. The regulatory mechanisms of this regeneration are not fully known. Liver regeneration· is associated with rapid growth and thereby increased demands for energy and synthesis of new compounds. READ MORE

  5. 5. Regulation of digestive organ. An experimental study on the role of CCK, Bile and EGF

    Author : Bodil Ohlsson; Internmedicin - epidemiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; trophic effects; total parenteral nutrition; salivary glands; pancreaticobiliary diversion; pancreas; liver; intestinal mucosa; epidermal growth factor; cholecystokinin; biliodigestive shunt; Bile; bilary tract; serology; transplantation; Immunologi; serologi; Gastro-enterology; Gastroenterologi;

    Abstract : Cholecystokinin (CCK) is known to exert secretory and trophic effects on the pancreas. Its release from the intestinal mucosa is regulated by pancresic proteases in the small intestine. However, knowledge about the type of responding exocrine cells and the time course of events during stimulation with CCK is lacking. READ MORE