Search for dissertations about: "Cholesterol"

Showing result 16 - 20 of 621 swedish dissertations containing the word Cholesterol.

  2. 16. Antimicrobial Peptide Interactions with Phospholipid Membranes : Effects of Peptide and Lipid Composition on Membrane Adsorption and Disruption

    Author : Adam A Strömstedt; Martin Malmsten; Georges Belfort; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antimicrobial; peptide; adsorption; liposome; membrane; melittin; cholesterol; tryptophan; phospholipid; bilayer; PHARMACY; FARMACI; Pharmaceutical Physical Chemistry; farmaceutisk fysikalisk kemi;

    Abstract : The interactions between antimicrobial peptides and phospholipid membranes were investigated, in terms of lipid headgroup variations and the role of cholesterol, as well as peptide composition and structure. Also strategies for increasing proteolytic stability were evaluated. READ MORE

  4. 17. Molecular mechanisms in obesity-associated metabolic disease

    Author : Louise Olofsson; Göteborgs universitet; []
    Keywords : obesity; metabolic syndrome; cholesterol; resting metabolic rate; insulin resistance; serum amyloid A; S100 calcium binding protein A1; Zn-alpha2-glycoprotein; CCAAT enhancer binding protein alpha;

    Abstract : Obesity is associated with increased morbidity and mortality. Subjects with obesity are at risk of developing several serious conditions such as type 2 diabetes, hypertension, coronary heart disease and stroke. READ MORE

  5. 18. Phosphoinositides control insulin secretion through multiple routes

    Author : Phuoc My Nguyen; Christina Bark; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Phosphoinositides; PI 4 P; PI 4; 5 P2; Ca2 ; optogenetics; VDCC; Sac2; OSBP; OSW-1; cholesterol; membrane contact sites;

    Abstract : Glucose-stimulated insulin secretion from pancreatic beta cells is the sequence of events that starts with glucose uptake and ends with the fusion of insulin granules with the plasma membrane through Ca2+-triggered exocytosis. Phosphoinositides are minor components of all cellular membranes, yet play fundamental roles as regulators of many cellular processes. READ MORE

  6. 19. Molecular Dynamic Simulations of Biological Membranes

    Author : Qaiser Waheed; Olof Edholm; Friederike Schmid; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; phospholipids; area compressibility; undulations; quantum corrections; cholesterol; phase transition; segregation;

    Abstract : Biological membranes mainly constituent lipid molecules along with some proteins and steroles. The properties of the pure lipid bilayers as well as in the presence of other constituents (in case of two or three component systems) are very important to be studied carefully to model these systems and compare them with the realistic systems. READ MORE

  7. 20. The Impact of Birth Weight on Cardiovascular Risk Factors, Coronary Heart Disease and Prostate Cancer : Population-based Studies of Men Born in 1913 and Followed up Until Old Age

    Author : Margaretha Eriksson; Kurt Svärdsudd; Lena Hulthén; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; birth weight; coronary heart disease; cardiovascular disease; diabetes; blood pressure; hypertension; cholesterol; prostate cancer; cohort studies; follow-up studies; Family medicine; Allmänmedicin;

    Abstract : Objectives. To study whether birth weight (BW) was correlated to cardiovascular risk factors, coronary heart disease (CHD), cardiovascular disease (CVD), and prostate cancer (PCA) at adult ages, whether a possible relationship depended on mediating factors from birth time, hereditary circumstances, and adult life variables, and what importance possible associations might have for the rate of the complaint in the general population. READ MORE