Search for dissertations about: "Christer Betsholtz"

Showing result 1 - 5 of 10 swedish dissertations containing the words Christer Betsholtz.

  2. 1. Role of platelet-derived growth factor in neoplastic transformation

    Author : Christer Betsholtz; Uppsala universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : .... READ MORE

  4. 2. Cdc42, orchestrator of vascular morphogenesis in the retina

    Author : Alberto Álvarez-Aznar; Konstantin Gängel; Christer Betsholtz; Taija Mäkinen; Ondine Cleaver; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Cdc42; endothelial cell; pericyte; mural cell; angiogenesis; CreERT2; Medicinsk vetenskap; Medical Science;

    Abstract : Cdc42 is a small GTPase that controls many cellular functions related to cytoskeletal dynamics, such as migration, polarity, and proliferation. Despite what we know of Cdc42 in other cell types, not much research has been done on the vasculature. READ MORE

  5. 3. Cellular and molecular roles for CDC42 in angiogenesis

    Author : Marco Castro; Christer Betsholtz; Bàrbara Laviña; Rui Benedito; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CDC42; angiogenesis; endothelial cell; vascular malformation; Biology with specialization in Molecular Cell Biology; Biologi med inriktning mot molekylär cellbiologi;

    Abstract : Angiogenesis is the physiological process by which new blood vessels grow and critically depends on the interplay between the major vascular units: endothelial cells, pericytes and smooth muscle cells. Dysfunction and mispatterning of blood vessels are associated with the progression of many vascular complications, and therefore, understanding the causes of vascular dysmorphia is a central question in vascular biology. READ MORE

  6. 4. Neural Stem Cell Differentiation and Migration

    Author : Anna Erlandsson; Karin Forsberg-Nilsson; Bengt Westermark; Christer Betsholtz; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; CNS; stem cells; neuron; PDGF; SCF; differentiation; migration; ERK; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; Medicinsk biokemi; Medical Biochemistry;

    Abstract : Neural stem cells are the precursors of neurons, astrocytes and oligodendrocytes. During neural development, the division of stem cells takes place close to the lumen of the neural tube, after which they migrate to their final positions within the central nervous system (CNS). READ MORE

  7. 5. The role of PDGF-A in lung development, injury and repair

    Author : Leonor Gouveia; Johanna Andrae; Christer Betsholtz; Brigid Hogan; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Lung; organogenesis; PDGF; signalling pathway; development;

    Abstract : The developmental processes that take place during embryogenesis depend on a great number of proteins that are important for cell-to-cell communication. Platelet-derived growth factors are known to be important for epithelial-mesenchymal interactions during development and organogenesis. READ MORE