Search for dissertations about: "Christian Cambillau"

Found 2 swedish dissertations containing the words Christian Cambillau.

  2. 1. Structural and Biochemical Characterizations of Three Potential Drug Targets from Pathogens

    Author : Lu Lu; Sherry L Mowbray; Alwyn Jones; Christian Cambillau; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LepB; DXR; NDH-2; fosmidomycin; quinolinyl pyrimidine; Biology with specialization in Structural Biology; Biologi med inriktning mot strukturbiologi;

    Abstract : As antibiotic resistance of various pathogens emerged globally, the need for new effective drugs with novel modes of action became urgent. In this thesis, we focus on infectious diseases, e.g. READ MORE

  4. 2. Structural Plasticity and Function in Cytochrome cd1 Nitrite Reductase

    Author : Tove Sjögren; Christian Cambillau; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; cytochrome cd1; nitrite reductase; oxidase; redox protein; electron transfer; proton transfer; X-ray crystallography; Biokemi; Biochemistry; Biokemi; biokemi; Biochemistry;

    Abstract : Cytochrome cd1 nitrite reductase is a bifunctional enzyme, which catalyses the one-electron reduction of nitrite to nitric oxide, and the four-electron reduction of oxygen to water. The latter is a cytochrome oxidase reaction. Both reactions occur on the d1 haem iron of the enzyme. READ MORE