Search for dissertations about: "Christian Hedberg"

Found 5 swedish dissertations containing the words Christian Hedberg.

  1. 1. Synthesis and investigation of bacterial effector molecules

    Author : Michael Franz Albers; Christian Hedberg; Christian Hackenberger; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; bacterial effectors; organic synthesis; Legionella; PTM; peptide synthesis; nucleotide chemistry; Biorganic Chemistry; bioorganisk kemi;

    Abstract : During infections, bacterial microorganisms initiate profound interactions with mammalian host cells. Usually defense mechanisms of the host destroy intruding bacteria in rapid manner. However, many bacterial pathogens have evolved in a way to avoid these mechanisms. READ MORE

  2. 2. Design, Synthesis, Mechanistic Rationalization and Application of Asymmetric Transition-Metal Catalysts

    Author : Christian Hedberg; Pher G. Andersson; Hans-Ulrich Blaser; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; asymmetric catalysis; homogeneous hydrogenation; iridium; ruthenium; ligand design; mechanistic studies; kinetics; tolterodine; Organisk kemi; Organic chemistry; Organisk kemi;

    Abstract : This thesis describes mechanistic studies, rational ligand design, and synthesis of asymmetric transition metal catalysts. The topics addressed concerned [Papers I-VII]:[I] The asymmetric addition of diethyl zinc to N-(diphenylphosphinoyl)benzalimine catalyzed by bicyclic 2-azanorbornyl-3-methanols was studied. READ MORE

  3. 3. Studies on Phosphohistidine Phosphatase 1 : What? Where? Why?

    Author : Ulla Beckman Sundh; Pia Ek; Örjan Zetterqvist; Jin-ping Li; Christian Hedberg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PHPT1; Phosphohistidine phosphatase; PHP; Assay; Medical Biochemistry; Medicinsk biokemi;

    Abstract : Phosphohistidine phosphatase 1 (PHPT1) is a small protein, consisting of 125 amino acids, that catalyzes the dephosphorylation of histidine but does not have any activity towards other phosphorylated amino acids. PHPT1 was identified in 2002, and is so far the only mammalian histidine phosphatase known, but still little is known about its physiological role. READ MORE

  4. 4. Selective protein functionalisation via enzymatic phosphocholination

    Author : Philipp Ochtrop; Christian Hedberg; Tom Grossmann; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; chemical biology; organic synthesis; site-selective protein labeling; PTM; phosphocholination; nucleotides; bioorthogonal chemistry; proteomics; IMPDH2;

    Abstract : Proteins are the most abundant biomolecules within a cell and are involved in all biochemical cellular processes ultimately determining cellular function. Therefore, to develop a complete understanding of cellular processes, obtaining knowledge about protein function and interaction at a molecular level is critical. READ MORE

  5. 5. Outside the World : Cohesion and Deviation among Old Colony Mennonites in Bolivia

    Author : Anna Sofia Hedberg; Jan-Åke Alvarsson; Bengt G. Karlsson; Lars Hagborg; Simon Coleman; Uppsala universitet; []
    Keywords : Cultural anthropology; Old Colony Mennonites; community; social cohesion; boundary maintenance; margins; trans-cultural interaction; deviation; anthropology of religion; migration; Bolivia; Kulturantropologi;

    Abstract : This study is about community maintenance and social cohesion among Old Colony Mennonites in Bolivia. The Old Colony Mennonites constitute a Christian minority that traces its origin to the European Anabaptist movement of the 16th century. READ MORE