Search for dissertations about: "Christine Wegler"

Found 1 swedish dissertation containing the words Christine Wegler.

2. 1. Proteomics-informed analysis of drug disposition in the human liver and small intestine

   Author : Christine Wegler; Per Artursson; Pär Matsson; Tommy B Andersson; Manthena Varma; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; proteomics; protein concentration; drug disposition; drug transport; drug metabolism; human small intestine; human liver; human hepatocytes; human liver microsomes; inter-individual variability; drug clearance; obesity; prediction model; Farmaceutisk vetenskap; Pharmaceutical Science;

   Abstract : Orally administered drugs are absorbed in the intestine and generally metabolized in the liver. Therefore, understanding factors determining drug distribution and elimination in these tissues is important. READ MORE