Search for dissertations about: "Christoph Rader"

Found 2 swedish dissertations containing the words Christoph Rader.

2. 1. Affibody-mediated targeting of HER-family receptors for cancer imaging and therapy

   Author : Charles Dahlsson Leitao; Stefan Ståhl; John Löfblom; Christoph Rader; KTH; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer therapy; radionuclide imaging; affibody molecules; HER-receptors; prodrug; protein design; Cancerterapi; radionuklidavbildning; affibody molekyler; HER-receptorer; prodrog; proteindesign; Bioteknologi; Biotechnology;

   Abstract : Proteins are remarkable molecules with diverse and specialized functions playing essential roles in most biological processes. One such function is protecting us from diseases by the action of antibodies in our immune system that can recognize and mediate the destruction of invading pathogens by binding to foreign epitopes found on non-self proteins. READ MORE

4. 2. Generation and engineering of ABD-derived affinity proteins for clinical applications

   Author : Sarah Lindbo; Sophia Hober; Christoph Rader; KTH; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; ABD; ADAPT; affinity proteins; protein engineering; radionuclide molecular imaging; HER2; Bioteknologi; Biotechnology;

   Abstract : Proteins that specifically recognize and bind to other molecules or structures are important tools in industrial and medical applications. Binding proteins engineered from small stable scaffold proteins have been utilized for several purposes due to their favorable biophysical properties, tolerance to mutagenesis, efficient tissue penetration and ease of production. READ MORE