Search for dissertations about: "Christoph Varenhorst"

Found 3 swedish dissertations containing the words Christoph Varenhorst.

  1. 1. Platelet Inhibition in Coronary Artery Disease – Mechanisms and Clinical Importance : Studies with Focus on P2Y12 Inhibition

    Author : Christoph Varenhorst; Stefan James; Agneta Siegbahn; Lars Wallentin; Steen Dalby Kristensen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; coronary artery disease; myocardial infarction; acute coronary syndromes; stent thrombosis; P2Y12 inhibitors; thienopyridines; clopidogrel poor response; clopidogrel; prasugrel; Cardiology; Kardiologi; Kardiologi; Cardiology;

    Abstract : Despite the currently recommended dual antiplatelet treatment (DAT) with aspirin and P2Y12 inhibition in patients with coronary artery disease (CAD) there is a risk of adverse clinical outcome. Pharmacodynamic (PD) poor response to clopidogrel occurs in ~ 30% of clopidogrel-treated patients and is associated with an increased risk of recurrent thrombotic events. READ MORE

  2. 2. Invasive treatment of coronary artery disease : Aspects on antithrombotic and percutaneous treatment options

    Author : Per Grimfjärd; Stefan James; Christoph Varenhorst; P Hedberg; Lene Holmvang; Uppsala universitet; []
    Keywords : PCI; STEMI; stent thrombosis; bivalirudin; heparin; bioresorbable scaffold; cangrelor; drug eluting stent; DES; Cardiology; Kardiologi;

    Abstract : The outcome after percutaneous coronary intervention (PCI) has improved considerably thanks to more effective antithrombotic treatment strategies and improved coronary stents. Stent thrombosis (ST) is a rare complication to PCI associated with considerable mortality and morbidity. READ MORE

  3. 3. Platelet Inhibition, Revascularization, and Risk Prediction in Non-ST-elevation Acute Coronary Syndromes

    Author : Daniel Lindholm; Stefan James; Christoph Varenhorst; James de Lemos; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; coronary artery disease; myocardial infarction; acute coronary syndrome; non-ST-elevation acute coronary syndrome; P2Y12 inhibitors; ticagrelor; biomarkers; revascularization; percutaneous coronary intervention; risk prediction; Cardiology; Kardiologi;

    Abstract : Cardiovascular disease is the leading cause of death worldwide and ischemic heart disease is the most common manifestation. Despite improved outcomes during the last decades, patients with acute coronary syndromes (ACS) are still at substantial risk of recurrent ischemic events and mortality. READ MORE