Search for dissertations about: "Christopher Sjöwall"

Found 1 swedish dissertation containing the words Christopher Sjöwall.

  1. 1. C-reactive protein (CRP) and anti-CRP autoantibodies in systemic lupus erythematosus a study on the occurrence and clinical implications of anti-CRP antibodies and CRP-mediated complement activation

    University dissertation from Institutionen för molekylär och klinisk medicin

    Author : Christopher Sjöwall; Linköpings universitet.; Linköpings universitet.; [2006]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; autoantibodies; complement activation; C-reactive protein; cytokines; immune complex; immunoregulation; opsonization; systemic lupus erythematosus; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Internal medicine Rheumatology; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Invärtesmedicin Reumatologi;

    Abstract : Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by production of a wide range of autoantibodies, multiple organ involvement and by local formation or tissue deposition of immune complexes (ICs) in the inflamed organs. In contrast to most systemic inflammatory conditions, and despite raised levels of pro-inflammatory cytokines, SLE flares are rarely reflected by elevated C-reactive protein (CRP), an important acute-phase reactant in man with homologs in vertebrates and several invertebrates. READ MORE