Search for dissertations about: "Chromosomal Proteins"

Showing result 1 - 5 of 116 swedish dissertations containing the words Chromosomal Proteins.

  2. 1. Decoding the Structural Layer of Transcriptional Regulation : Computational Analyses of Chromatin and Chromosomal Aberrations

    Author : Robin Andersson; Jan Komorowski; Jan Dumanski; Claes Wadelius; Anders Krogh; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Chromatin; Nucleosome positioning; Histone modifications; Chromosomal aberrations; Transcriptional regulation; Array-CGH; Next generation sequencing; ChIP-chip; Bioinformatics; Bioinformatik; Bioinformatics; Bioinformatik;

    Abstract : Gene activity is regulated at two separate layers. Through structural and chemical properties of DNA – the primary layer of encoding – local signatures may enable, or disable, the binding of proteins or complexes of them with regulatory potential to the DNA. READ MORE

  4. 2. Outer membrane proteins of Yersinia pestis : Ail and OmpA

    Author : Sara Celinda Schesser Bartra; Hans Wolf-Watz; Virginia Miller; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Yersinia pestis; outer membrane proteins; Ail; ompA; Microbiology; immunology; infectious diseases; Mikrobiologi; immunologi; infektionssjukdomar; immunologi; Immunology; mikrobiologi; Microbiology; Infectious Diseases; infektionssjukdomar;

    Abstract : A vast number of studies have been completed on the virulence determinants of Yersinia spp.; however, the focus of many of these studies has been on the virulence plasmid and the plasmid-encoded Type three secretion system. Nevertheless, many chromosomal genes whose products are directly involved in virulence have also been identified. READ MORE

  5. 3. Immunodominant proteins in Giardia lamblia

    Author : Malin Weiland; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The protozoan parasite Giardia lamblia is a major cause of diarrhoea in humans and other mammals. Infection starts by ingestion of infectious cysts that excyst in the upper part of the small intestine and attach to intestinal epithelial cells. READ MORE

  6. 4. FET proteins in cancer and development

    Author : Mattias K Andersson; Göteborgs universitet; []
    Keywords : FUS; EWS; TAF15; FUS-DDIT3; myxoid liposarcoma; NF-κB; NFKBIZ; FLT1; CDK2;

    Abstract : Chromosomal translocations leading to rearrangements of FET family genes (FUS, EWSR1 and TAF15) are found in numerous human cancers. These genetic alterations result in the formation of fusion oncogenes that express potent chimeric oncoproteins able to promote tumor development. READ MORE

  7. 5. GGDEF-EAL domain proteins in bacterial physiology

    Author : Abdul Kader; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : GGDEF and EAL domain proteins were identified in the chromosome of many bacteria. GGDEF domain proteins are generally diguanyl cyclases which synthesize the secondary messenger cyclic di-GMP. EAL domain proteins are generally c-di-GMP specific phosphodiesterase which degrade c-di-GMP. READ MORE