Search for dissertations about: "Chromosomal aberrations"

Showing result 21 - 25 of 91 swedish dissertations containing the words Chromosomal aberrations.

  2. 21. Molecular cytogenetic investigations of chromosomal abnormalities in prostate and urinary bladder cancers

    Author : Yi Pan; Karolinska Institutet; Karolinska Institutet; []
    Keywords : prostate cancer; bladder cancer; FISH; SKY;

    Abstract : Tumorigenesis is suggested to be caused by base pair mutations and chromosomal abnormalities leading to inactivation of tumor suppressor genes an activation of oncogenes. However, still it is not clear for the vast majority of these changes how they contribute to the tumorigenesis of the prostate and bladder cancers. READ MORE

  4. 22. Effects of post-treatments with hydroxyurea and caffeine in G2 on the frequency of chromosomal aberrations induced by physical and chemical agents in mammalian cells

    Author : Kerstin Hansson; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP;

    Abstract : .... READ MORE

  5. 23. Analysis of chromosomal rearrangements and gene copy number changes in breast cancer cells

    Author : Pär Lundin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Genome changes in terms of numerical chromosomal aberrations and structural rearrangements, including deletions, amplifications and translocations, gradually accumulate in the genome during tumor development. These genomic changes are likely to play an important role in the process of tumor progression. READ MORE

  6. 24. Molecular genetics of kidney cancer : chromosomal regions of importance in the development of renal cell carcinoma

    Author : Rikard Erlandsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Carcinoma; renal cell Chromosomes; human; pair 3 Chromosome deletion Genes; suppressor; tumor Sequence analysis; DNA. Renal cell carcinoma RCC is a malignancy of the human kidney; occurring most commonlyduring the seventh and eighth decades of;

    Abstract : Renal cell carcinoma (RCC) is a malignancy of the human kidney, occurring most commonly during the seventh and eighth decades of life. The incidence is high in the Nordic countries and the five year survival is 40-50%. Smoking is a risk factor inferring a minor increase in risk. The best established risk factor is obesity. READ MORE

  7. 25. Integrative genomic and survival analysis of breast tumors

    Author : Szilard Nemes; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; biostatistics; cancer; survival analysis; gemonics; DNA copy number aberrations; messenger RNA;

    Abstract : With the continued accumulation of genomic data at ever increasing resolution the challenge ahead lies in reading out meaningful clinical/biological information form the data that can contribute to a better understanding of the cancerous process. The need for novel approaches, new statistical methods is therefore strong. READ MORE