Search for dissertations about: "Chromosomal abnormalities"

Showing result 11 - 15 of 48 swedish dissertations containing the words Chromosomal abnormalities.

  2. 11. Molecular genetics of kidney cancer : chromosomal regions of importance in the development of renal cell carcinoma

    Author : Rikard Erlandsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Carcinoma; renal cell Chromosomes; human; pair 3 Chromosome deletion Genes; suppressor; tumor Sequence analysis; DNA. Renal cell carcinoma RCC is a malignancy of the human kidney; occurring most commonlyduring the seventh and eighth decades of;

    Abstract : Renal cell carcinoma (RCC) is a malignancy of the human kidney, occurring most commonly during the seventh and eighth decades of life. The incidence is high in the Nordic countries and the five year survival is 40-50%. Smoking is a risk factor inferring a minor increase in risk. The best established risk factor is obesity. READ MORE

  4. 12. Prenatal diagnosis in routine antenatal care : a randomised controlled trial

    Author : Sissel Saltvedt; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Ultrasound; fetal ultrasonography; Down s syndrome; chromosomal disorder; nuchal translucency; genetic screening; prenatal diagnosis; abnormalities; gestational age; in vitro fertilization; fetometry; dating formulas; false positive reactions; anxiety;

    Abstract : Nuchal translucency (NT) measurement combined with maternal age has been shown to identify women at an increased risk of carrying a fetus with Down's syndrome (DS) more accurately than does maternal age alone. The aim of this study was to evaluate more widely the effects of two different strategies for prenatal diagnosis. READ MORE

  5. 13. Genetic studies in early embryos with emphasis on preimplantation genetic diagnosis

    Author : Erik Iwarsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : chromosomal abnormality 1 embryo fluorescent in situ hybridisation FISH 1 in vitro fertilisation IVF 1 preimplantation genetic diagnosis PGD ;

    Abstract : It has been estimated that as much as 70-80% of all human conceptions do not develop to term. A majority of clinically recognisable pregnancies, which are miscarried, contain chromosome abnormalities. However, data from very early embryo development are difficult to obtain. READ MORE

  6. 14. Genetic analysis of human astrocytic gliomas : xenografts as a research tool

    Author : Helena M Goike; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Cancer is a genetic disorder of somatic cells. An accumulation of genetic changes is believed to result in neoplastic transformation and malignant progression. In humans, astrocytic gliomas are the most common primary tumors of brain tissue. They are malignancy graded according to World Health Organization criteria. READ MORE

  7. 15. New molecular tools for prenatal diagnosis

    Author : Ellika Sahlin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Prenatal diagnosis enables identification of severe disease in the fetus, and allows for planning and management of future pregnancies if an underlying genetic mechanism is identified. The studies included in this thesis have taken advantage of the dramatic progress in medical genetics, in order to develop and evaluate new procedures to diagnose genetic disorders in fetal life. READ MORE