Search for dissertations about: "Chromosome architecture"

Showing result 6 - 10 of 23 swedish dissertations containing the words Chromosome architecture.

  2. 6. Coiled coil Cytoskeleton in Bacterial Cell Architecture : Studies of Growth and Development in Streptomyces

    Author : Sonchita Bagchi; Nora Ausmees; Joseph McCormick; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Coiled coil proteins; Bacterial cytoskeleton; Differentiation; Cell and molecular biology; Cell- och molekylärbiologi;

    Abstract : Bacterial cytoskeleton is an exciting and relatively new field of research. Recent findings have proven that microbes are well-organized and neatly structured organisms. READ MORE

  4. 7. Novel FISH methods to unveil genome architecture

    Author : Ana Mota; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The genome consists of incredibly long DNA strands that encode all the vital information for the cell to function. The DNA inclusion in the very tight nuclear space and, simultaneously, the establishment of a hierarchical organization of the chromatin that favors transcription of certain genes over others, sparked a long-lasting quest to understand the design principles that govern genome architecture. READ MORE

  5. 8. Microtubule and chromosome dynamics during mitosis in budding yeast

    Author : Alexander Julner Dunn; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : As a cell divides, DNA must be replicated and faithfully segregated between the mother and daughter cells. This segregation is facilitated by the mitotic spindle, assembled to pull sister chromatids apart as the cell divides. READ MORE

  6. 9. The impact of selection on the genetic architecture of complex traits

    Author : Tilman Rönneburg; Örjan Carlborg; Dirk-Jan De Koning; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biologi med inriktning mot populationsbiologi; Biology with specialization in Population Biology; Bioinformatik; Bioinformatics;

    Abstract : Accurate dissection of highly polygenic traits is difficult, in part due to the power required to identify and characterise minor loci, but also due to the potential nonadditive interactions between the contributing genetic variations within a population. This is often further complicated by the genetic features of natural or agricultural populations, where a good understanding of the genetic architecture of a quantitative trait, e. READ MORE

  7. 10. Regulation of chromatin transitions in the 3D architecture of the nucleus

    Author : Honglei Zhao; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The thesis explores the dynamic features and functions of chromatin crosstalk in the 3D nucleus space, with a focus on the regulation of chromatin transitions. In Paper I we employed the circular chromosome conformation capture assay (4C) and Chromatin in situ Proximity (ChrISP) technique to uncover an inter-chromosomal chromatin fiber interactome comprising both transcriptionally active circadian genes and repressed lamina-associated domains (LADs). READ MORE