Search for dissertations about: "Ckd with diabetes"

Showing result 1 - 5 of 34 swedish dissertations containing the words Ckd with diabetes.

2. 1. Genetics of Diabetes Subtypes. Characterization of novel cluster-based diabetes subtypes

   Author : Dina Mansour Aly; diabetes och endokrinologi Genomik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Precision medicine; Diabetes Subclassification; genome-wide association studies; GWAS; genetic risk scores; GRS; chronic kidney disease; CKD; diabetic kidney disease; DKD; Estimated glomerular filtration rate; eGFR; ANDIS; diabetes; diabetics;

   Abstract : BACKGROUND: Type 2 diabetes (T2D) has been reproducibly clustered into five subtypes based on six-clinical variables; age at diabetes onset, body mass index (BMI), Glutamic acid decarboxylase autoantibodies (GADA), glycated hemoglobin (HbA1c) and insulin secretion and resistance estimated as HOMA2B and HOMA2IR derived from fasting glucose and Cpeptide. These subtypes have different disease progression and risk of complications. READ MORE

4. 2. Fibroblast growth factor-23 and Klotho in bone/mineral and parathyroid disorders

   Author : Tijana Krajisnik; Tobias E. Larsson; Kenneth B. Jonsson; Östen Ljunggren; Peyman Björklund; Gunnar Sterner; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; calcitriol; chronic kidney disease; CKD; chronic renal failure; fibroblast growth factor 23; fibroblast growth factor-23; FGF23; FGF-23; GalNac-T3; GALNT3; GFR; hyperostosis-hyperphosphatemia syndrome; HHS; Klotho; parathyroid hormone; PTH; hyperparathyroidism; pHPT; sHPT; uremic; vitamin D3; Endocrinology; Endokrinologi; Internal Medicine; invärtesmedicin;

   Abstract : Fibroblast growth factor-23 (FGF23) is a novel, bone-produced hormone that regulates renal phosphate (Pi) reabsorption and calcitriol metabolism. Disorders of mineral and bone metabolism, such as autosomal dominant hypophosphatemic rickets (ADHR) and hyperostosis-hyperphosphatemia syndrome (HHS), witness the importance of well-balanced serum levels of FGF23. READ MORE

5. 3. Aspects of ethnicity on blood pressure regulating mechanisms and kidney function in a defined population

   Author : Christopher Nilsson; Allmänmedicin och samhällsmedicin; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glomerular filtration rate GFR ; Renal function; Ethnicity; biomarker; Pro-enkephalin; Blood pressure; chronic kidney disase; ANDIS; diabetes; diabetics;

   Abstract : Background: Middle Eastern immigrants represent a growing population in Sweden today. This group are at higher risk for type 2 diabetes than the native population, but are also shown to exhibit unique properties; despite an abundance in traditional cardiometabolic risk factors such as obesity, dearranged blood lipids and diminished physical acitivity, this group seem to exhibit lower blood pressure levels. READ MORE

6. 4. Clinical consequences after heart transplantation with reference to osteoporosis, renal function, and immunosuppression. Experiences from Skåne University Hospital in Lund 1988-2019

   Author : Eveline Löfdahl; Kardiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heart Transplantation; Osteoporosis; chronic kidney disase; immunosuppressive agents;

   Abstract : Background. Heart transplantation (HT) remains the ultimate final therapy for patients with end-stage heart failure. To prevent rejection of the allograft, life-long immunosuppressive therapy is required. READ MORE

7. 5. The relationship between reduced renal function and cardiovascular disease

   Author : Patrik Svensson; Kardiovaskulär forskning - hypertoni; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; eGFR; creatinine; cystatin C; CKD-EPI; CKD; CVD; Genetics; Blood Pressure; Hypertension;

   Abstract : This thesis examines the relationship between measures of renal function and cardiovascular disease (CVD) in patients with hypertension (the NORDIL study) and in the healthy population (Malmö Diet and Cancer Study, MDC) and whether antihypertensive treatment response and the risk of CVD is affected by genetic variation of a regulator of the renal amiloroide sensitive sodium channel (NORDIL). In study 1 we tested creatinine, estimated glomerular filtration rate (eGFR) with Cockroft-Gault (CG) and the MDRD equations and also microalbuminuria (MA) as predictors of CVD, stroke and CVD death. READ MORE