Search for dissertations about: "Clinical biology Klinisk biologi neuroblastoma multidrug resistance hypoxia glucose-deficiency cell death Bax Apoptosis arsenic trioxide"

Found 1 swedish dissertation containing the words Clinical biology Klinisk biologi neuroblastoma multidrug resistance hypoxia glucose-deficiency cell death Bax Apoptosis arsenic trioxide.

  1. 1. Effects of arsenic trioxide and hypoxia in multidrug-resistant neuroblastoma

    Author : Jenny Karlsson; Institutionen för translationell medicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk biologi; Clinical biology; neuroblastoma; multidrug resistance; hypoxia; glucose-deficiency; cell death; Bax; Apoptosis; arsenic trioxide;

    Abstract : Neuroblastoma is a childhood tumour derived from the sympathetic nervous system. Although most children with neuroblastoma initially respond to treatment, approximately 50% of these patients relapse with multidrug-resistant tumours. Arsenic trioxide (As2O3) has been used for centuries to treat different clinical disorders including malignancies. READ MORE