Search for dissertations about: "Clinical chemistry"

Showing result 21 - 25 of 250 swedish dissertations containing the words Clinical chemistry.

  2. 21. Sources of preanalytical error in primary health care : implications for patient safety

    Author : Johan Söderberg; Christine Brulin; Ewa Idvall; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; blood specimen collection; haemolysis; medical errors; phlebotomy; preanalytical; primary health care; quality indicators; quality of health care; questionnaires; specimen handling; Clinical chemistry; Klinisk kemi; medicin; Medicine;

    Abstract : Background Venous blood tests constitute an important part in the diagnosis and treatment of patients. However, test results are often viewed as objective values rather than the end result of a complex process. This has clinical importance since most errors arise before the sample reaches the laboratory. READ MORE

  4. 22. Manipulation of potassium ion fluxes to induce apoptosis in lung cancer cells

    Author : Britta Andersson; Kjell Grankvist; Parviz Behnam-Motlagh; Roger Henriksson; Ola Brodin; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Apoptosis; Cisplatin; Intracellular K content; Mesothelioma; Na K ATPase pump; Clinical chemistry; Klinisk kemi;

    Abstract : Apoptosis is a special form of cell death that if non-functional may lead to diseases such as cancer. A reduction of the intracellular potassium ion (K+) content is necessary for activating enzymes important for the execution of apoptosis. READ MORE

  5. 23. Preanalytical errors in hospitals : implications for quality improvement of blood sample collection

    Author : Olof Wallin; Christine Brulin; Kjell Grankvist; Johan Hultdin; Bethany van Guelpen; Ania Willman; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; medical errors; preanalytical; quality improvement; questionnaire; venous blood sampling; Clinical chemistry; Klinisk kemi;

    Abstract : Background: Most errors in the venous blood testing process are preanalytical, i.e. they occur before the sample reaches the laboratory. Unlike the laboratory analysis, the preanalytical phase involves several error-prone manual tasks not easily avoided with technological solutions. READ MORE

  6. 24. Bacterial toxins for cancer treatment

    Author : David Johansson; Parviz Behnam-Motlagh; Kjell Grankvist; Anders Johansson; Roger Henriksson; Bo Baldetorp; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alpha‐toxin; AC‐toxin; mesothelioma; lung cancer; glioma; breast cancer; caspases; MAP-Kinase; verotoxin‐1; cisplatin; apoptosis; Gb3; drug resistance; Clinical chemistry; Klinisk kemi;

    Abstract : Even though anti‐cancer chemotherapy has been continuously improved during the last decades. problems with adverse effects and drug resistance still constitutes a considerable obstacle and sets a demand for new effective treatment options. READ MORE

  7. 25. Studies on Tissue Factor with Focus on Cell Signaling and Cancer

    Author : Oskar Eriksson; Agneta Siegbahn; Lina Badimon; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Tissue Factor; blood coagulation; cell signaling; protease; mass spectrometry; immunohistochemistry; colorectal cancer; apoptosis; Eph receptor; Klinisk kemi; Clinical Chemistry; Molekylär cellbiologi; Molecular Cellbiology;

    Abstract : This thesis have explored the functions of the protein Tissue Factor (TF), which together with its ligand coagulation factor VII/VIIa (FVII/FVIIa) forms a proteolytic complex that functions in initiation of blood coagulation and activation of cell signaling.In paper I, the mechanisms behind the observation that TF/FVIIa signaling protects cells from apoptosis were further investigated. READ MORE