Search for dissertations about: "Clinical sample"

Showing result 1 - 5 of 874 swedish dissertations containing the words Clinical sample.

  2. 1. The future of clinical trials for Alzheimer's disease. A blood-based biomarker perspective

    Author : Nicholas Cullen; Klinisk minnesforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer s disease; Biomarkers; Cognition; Amyloid; Tau; Neurodegeneration;

    Abstract : Objectives: The primary objective was to investigate the utility of blood-basedbiomarkers of amyloid, tau, and neurodegeneration for (i) screening, (ii)enrichment, and (iii) tracking response to treatment in clinical trials of Alzheimer’sdisease.Methods: Longitudinal, participant-level data used in these studies was drawn fromthe Swedish BioFINDER study and the ADNI study. READ MORE

  4. 2. Use of secondary preventive drugs after stroke

    Author : Maria Sjölander; Eva-Lotta Glader; Rune Dahlqvist; Marie Eriksson; Björn Wettermark; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; stroke; secondary prevention; drug use; equality; medication adherence; medication beliefs; medicin; Medicine; klinisk farmakologi; Clinical Pharmacology; samhällsfarmaci; Social Pharmacy;

    Abstract : Background Stroke is a serious condition that can have significant impact on an individual’s health and is a significant burden on public health and public finances. Secondary preventive drug treatment after stroke is important for decreasing the risk of recurrent strokes. READ MORE

  5. 3. Adolescent mental health : time trends and validity of self-report measures

    Author : Ida Blomqvist; Eva Henje; Inga Dennhag; Anne Hammarström; Lotte Haverman; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adolescent; classical test theory; computer adaptive testing; cross-sectional; differential item functioning; graded response model; item banks; item response theory; measurement invariance; mental health; Patient-Reported Outcomes Measurement Information System; Reynolds Adolescent Depression Scale second edition; self-report measures; time trends; barn- och ungdomspsykiatri; Child and Youth Psychiatry;

    Abstract : Background: Studies of time trends of adolescent self-reported mental health suggest an increase of mental health symptoms globally. Unfortunately, several studies within the field have methodological problems, such as short time-period between measurements and different mental health measures over time. READ MORE

  6. 4. Preanalytical errors in hospitals : implications for quality improvement of blood sample collection

    Author : Olof Wallin; Christine Brulin; Kjell Grankvist; Johan Hultdin; Bethany van Guelpen; Ania Willman; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; medical errors; preanalytical; quality improvement; questionnaire; venous blood sampling; Clinical chemistry; Klinisk kemi;

    Abstract : Background: Most errors in the venous blood testing process are preanalytical, i.e. they occur before the sample reaches the laboratory. Unlike the laboratory analysis, the preanalytical phase involves several error-prone manual tasks not easily avoided with technological solutions. READ MORE

  7. 5. Insomnia Symptoms in Chronic Pain : Clinical presentation, risk and treatment

    Author : Tobias Wiklund; Elena Dragioti; Steven J. Linton; Björn Gerdle; Péter Alföldi; Bjørn Bjorvatn; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : In recent years, chronic and recurrent pain have gained interest as distinct conditions interacting both with peripheral and central parts of the nervous system as well as with the immune system. The risk of getting affected by abnormal pain modulation i.e. READ MORE