Search for dissertations about: "Clonidine in spinal"

Showing result 1 - 5 of 7 swedish dissertations containing the words Clonidine in spinal.

2. 1. Perioperative effects of systemic or spinal clonidine as adjuvant during spinal anaesthesia

   Author : Igor Dobrydnjov; Torsten Gordh Jr.; Linköpings universitet; []
   Keywords : MEDICINE; MEDICIN;

   Abstract : Aim of study: To evaluate the effects of different doses of clonidine administered systemically or spinally in combination with local anaesthetics on sensory and motor block intraoperatively, on pain relief postoperatively, and on the incidence of postoperative alcohol withdrawal syndrome (AWS) in alcohol abusers.Patients and methods: A total 285 patients were included in five studies. READ MORE

4. 2. Advances in spinal cord stimulation : enhancement of efficacy, improved surgical technique and a new indication

   Author : Göran Lind; Karolinska Institutet; Karolinska Institutet; []
   Keywords : spinal cord stimulation;

   Abstract : Introduction and aim: Spinal cord stimulation (SCS) has been used for treatment of otherwise therapy-resistant chronic neuropathic pain for about four decades. However, 30-40 % of the patients do not benefit from SCS, despite careful case selection and technical advances. READ MORE

5. 3. Nerve injury induced pain and spinal cord stimulation

   Author : Camilla Ultenius; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Neuropathic pain;

   Abstract : Chronic neuropathic pain caused by injury to or disease in the nervous system is relatively common and results in major suffering, poor quality of life and incapacity. Such pain is a therapeutic challenge because a considerable portion of the patients fails to benefit from pharmacotherapy. READ MORE

6. 4. Treatment of pain behavior after spinal cord injury in rats with special emphasis on the role of adenosine receptors

   Author : Margareta von Heijne; Karolinska Institutet; Karolinska Institutet; []
   Keywords : adenosine; adenosine receptors; allodynia; baclofen; central pain; clonidine; intrathecal; morphine; neuropathic pain; opioid; rat; R-phenylisopropyladenosine; spinal cord injury; tolerance;

   Abstract : Central pain is a form of neuropathic pain occurring after injury or dysfunction in the central nervous system, including the spinal cord. Allodynia (pain to innocuous stimuli) to mechanical and cold stimulation is a common feature of central pain and it is often resistant to treatment. READ MORE

7. 5. Drug-enhanced spinal cord stimulation for neuropathic pain : studies on neurochemical mechanisms and clinical applications

   Author : Gastón Schechtmann; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Acetylcholine; baclofen; cholinergic analgesia; clonidine; gabapentin; neuropathic pain; nerve injury; pregabalin; spinal cord stimulation; intrathecal drug;

   Abstract : Spinal cord stimulation (SCS) is an effective surgical treatment for neuropathic pain refractory to pharmacological therapy. For many patients suffering from this type of chronic pain, SCS is in fact the ultimate treatment option. READ MORE