Search for dissertations about: "Coarse-grained modelling"
Showing result 1 - 5 of 11 swedish dissertations containing the words Coarse-grained modelling.
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1. Coarse-Grained Modelling of Protein Adsorption
Abstract : The adsorption of proteins is a very common phenomenon, happening almost always when a protein solution comes into contact with a solid. However, it is far from always clear what the results of adsorption will be in terms of adsorbed amount, protein orientation, and protein conformation. READ MORE
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2. Assessing self-association of intrinsically disordered proteins by coarse-grained simulations and SAXS
Abstract : This research investigates the behavior of intrinsically disordered proteins (IDPs) in solution, especially the self-associating saliva protein Statherin, by a combined computational and experimental approach. For the computational part, a bead necklace model previously parameterised for Histatin 5 was used. READ MORE
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3. Coarse-grained and atomistic modelling of phosphorylated intrinsically disordered proteins
Abstract : Intrinsically disordered proteins (IDPs) are involved in many biological processes such as signalling, regulation and recognition. One of the main questions regarding IDPs is how sequence, structure and function are related. READ MORE
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4. Modelling the Protein-DNA Interface
Abstract : Protein-DNA interactions are crucial to life. Several millions of DNA base pair steps are organ- ised, read and protected by proteins in every cell. Protein-DNA interactions must be specific, controllable and reasonably fast. Understanding how these features coexist is one of the great challenges for biochemists and molecular biologists. READ MORE
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5. Modelling Biomolecular Interactions of Protein Solutions : Combining Theories and Experiments
Abstract : Nowadays, interactions of proteins in salt solutions and at the interface with inorganic surfaces are widely investigated as their understanding has numerous applications in medical, pharmaceutical, and biotechnological industries. However, studying these interactions is a complex task that requires appropriate strategies. READ MORE