Search for dissertations about: "Colon signal"
Showing result 1 - 5 of 21 swedish dissertations containing the words Colon signal.
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1. Neuro-immune regulation of macromolecular permeability in the normal human colon and in ulcerative colitis
Abstract : Background and aim: Persistent stress and life events affect the course of ulcerative colitis (UC) by largely unknown mechanisms. Regulation of epithelial permeability to antigens is crucial for the balance between inflammation and immuno-surveillance, and increased intestinal permeability has been shown in patients with ulcerative colitis. READ MORE
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2. HER3 expression and prognosis in colon and rectal cancer
Abstract : In Sweden, about 6000 patients get a colorectal cancer diagnosis annually. Advances in management of both colon and rectal cancer have reduced mortality even though the incidences are increasing. READ MORE
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3. Crosstalk between colorectal cancer cells and tumour-associated macrophages
Abstract : Colorectal cancer (CRC) is the third most common cancer and the fourth leading cause of death from cancer worldwide. People suffering from inflammatory bowel disease, such as Crohns’ disease and ulcerative colitis, are at an increased risk of developing CRC. The development of CRC is highly influenced by the tumour microenvironment. READ MORE
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4. Expression and novel function of CD43 in colon cancer cells
Abstract : CD43 is a transmembrane protein containing an extracellular domain that is extensively O-glycosylated, and a relatively large intracellular domain with a conserved sequence between human, rat and mouse. It is frequently expressed in haematopoietic cell lines where it functions as a regulator of cell adhesiveness, a signal transducer and a cytoskeleton-interacting protein. READ MORE
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5. Radioimmunotherapy of Metastatic Disease - Studies of Alpha- and Beta-particle-Emitting Radionuclides in a Preclinical Model
Abstract : In radioimmunotherapy, monoclonal antibodies (mAbs) are used as a targeting agent carrying a toxic payload consisting of radionuclides. This treatment allows the irradiation of small lesions, even on the microscopic level. In the present work, two radionuclides with different properties were used. READ MORE