Search for dissertations about: "Comparative study of two recent drugs"

Found 2 swedish dissertations containing the words Comparative study of two recent drugs.

  1. 1. Molecular mechanisms and targets of new anticancer treatments

    Author : Amirata Saei Dibavar; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The work presented in this thesis is an effort to decipher and understand the mechanism of action (MOA) of anticancer agents by building on and complementing chemical proteomics methods. The backbone of the thesis relies on a recent method called Functional Identification of Target by Expression Proteomics (FITExP) developed in Zubarev lab, where drug induced proteomic signatures are analyzed in various cell lines and top differentially regulated proteins with consistent behavior are determined, among which the drug target and mechanistic proteins are usually present. READ MORE

  2. 2. Pleurodesis in chronic effusions : studies on inflammatory mediators, respiratory function, predictability of treatment outcome, drug efficiency and survival after treatment

    Author : Valiant Ukale; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Metastatic or primary (mesothelioma) malignancy of the pleura often generates major pleura] effusion, giving respiratory distress and low quality of life to the patients. Evacuation of fluid by thoracocentesis gives only temporary relief, therefore pleurodesis is generally regarded the best way to give palliation. READ MORE