Search for dissertations about: "Complement C3"
Showing result 1 - 5 of 80 swedish dissertations containing the words Complement C3.
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1. The complement system in stherosclerosis and arthritis
Abstract : The complement system plays an essential role in the humoral immune response. Activated complement has diverse functions, including the initiation of inflammation, recruitment of leukocytes, clearance of immune complexes, neutralization of pathogens, regulation of antibody responses and disruption of cell membranes. READ MORE
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2. Crosstalk Between Activated Platelets and the Complement System
Abstract : Several studies have shown that complement and thrombotic events co-exist. Platelets have been suspected to act as the bridge between the two cascade systems. READ MORE
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3. The role of the complement system in arthritis and stroke
Abstract : Complement is part of the innate immune system and functions primarily as a first line of defense against invading microorganisms. It is a complex cascade, which can be activated via three pathways: the classical, alternative and mannan-binding lectin pathway. READ MORE
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4. Analysis of Complement Deficiency States. With Focus on Molecular Characterization of C4 and Properdin Deficiency
Abstract : Complement deficiency is associated with an increased risk for invasive infection and immune complex disease. Screening for identification of complement-deficient patients is essential and a new ELISA-based procedure for detection of complement deficiency is described. READ MORE
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5. Complement in Disease - Extracellular Proteins as Complement Regulators
Abstract : Complement activation occurs during inflammatory joint diseases such as rheumatoid arthritis (RA) and is thought to contribute to the chronic inflammation observed within the joints. Previous studies have shown that certain cartilage components of the small leucine-rich repeat protein (SLRP)-family regulate complement activity, thereby possibly contributing to disease progression. READ MORE