Search for dissertations about: "Complement C4"

Showing result 1 - 5 of 24 swedish dissertations containing the words Complement C4.

  2. 1. Analysis of Complement Deficiency States. With Focus on Molecular Characterization of C4 and Properdin Deficiency

    Author : Gunilla Nordin Fredrikson; Kardiovaskulär forskning - immunitet och ateroskleros; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mycology; virology; bacteriology; Complement C4; Complement; Complement Screening; Deficiency; Meningococcal Disease; Properdin; Properdin Expression; Microbiology; Sequencing; Mikrobiologi; bakteriologi; virologi; mykologi;

    Abstract : Complement deficiency is associated with an increased risk for invasive infection and immune complex disease. Screening for identification of complement-deficient patients is essential and a new ELISA-based procedure for detection of complement deficiency is described. READ MORE

  4. 2. The Role of IgM and Complement in Antibody Responses

    Author : Christian Rutemark; Birgitta Heyman; Claus Nielsen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Complement; antibody response; mutated IgM; natural IgM; complement receptors; SIGN-R1; SAP; CRP; B cells; Medical Science; Medicinsk vetenskap;

    Abstract : An intact complement system including the complement receptors 1 and 2 (CR1/2) is crucial for the generation of a normal antibody response in animals and humans. Moreover, activation of the classical pathway is thought to be important since deficiency in complement components C1q, C2, C4 or C3 lead to impaired antibody responses. READ MORE

  5. 3. Crosstalk Between Activated Platelets and the Complement System

    Author : Osama A. Hamad; Bo Nilsson; Kristina Ekdahl-Nilsson; Lennart Truedsson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; platelets; activated platelets; TRAP; chondroitin sulfate; C1q; factor H; C4BP; C3; Compstatin; complement; platelet-leukocyte complexes; platelet microparticles; Clinical immunology; Klinisk immunologi; Klinisk immunologi; Clinical Immunology;

    Abstract : Several studies have shown that complement and thrombotic events co-exist. Platelets have been suspected to act as the bridge between the two cascade systems. READ MORE

  6. 4. Synaptic elimination and the complement system in Alzhaimer's disease

    Author : Jonny Daborg; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Synapse; Alzheimer s disease; Genetics; CSF; Complement; RAGE;

    Abstract : The mechanisms behind Alzheimer’s disease (AD) are largely unknown. The disease is to a large extent hereditary, and the best pathophysiological correlate to the severity of the symptoms is loss of synapses. READ MORE

  7. 5. Complement-dependent defence against bacterial infection. Studies in C2 deficiency

    Author : Barbro Selander; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antibody responses; polysaccharide antigens; vaccination; mannan-binding lectin MBL ; complement; C2 deficiency; Immunology; serology; transplantation; Immunologi; serologi;

    Abstract : The complement system is critically involved in defence against bacterial infection. C2 deficiency is, apart from mannan-binding lectin (MBL) deficiency, the most common homozygous complement deficiency among Caucasians. READ MORE