Search for dissertations about: "Conformational selection"
Showing result 1 - 5 of 18 swedish dissertations containing the words Conformational selection.
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1. Computational Study of Calmodulin’s Ca2+-dependent Conformational Ensembles
Abstract : Ca2+ and calmodulin play important roles in many physiologically crucial pathways. The conformational landscape of calmodulin is intriguing. Conformational changes allow for binding target-proteins, while binding Ca2+ yields population shifts within the landscape. Thus, target-proteins become Ca2+-sensitive upon calmodulin binding. READ MORE
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2. The CD40 Receptor - Target,Tool and Technology
Abstract : CD40 is a cell surface receptor of pivotal importance that is expressed on several of the cells in the immune system. It is critical for many important events, such as T cell dependent B cell activation, isotype switching, somatic mutation and generation of B cell memory. READ MORE
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3. Galectin-3 Ligand Binding: Mechanism and Driving Forces
Abstract : .... READ MORE
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4. Studies on the functional interaction of translation initiation factor IF1 with ribosomal RNA
Abstract : Translation initiation factor IF1 is a small, essential and ubiquitous protein factor encoded by a single infA gene in bacteria. Although several important functions have been attributed to IF1, the precise reason for its indispensability is yet to be defined. READ MORE
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5. Small angle scattering as a tool to study protein structure and interactions
Abstract : This thesis uses small angle X-ray and neutron scattering (SAXS/SANS) to gain structural and functional insight into the molecular regulation of critical life processes in prokaryotic and eukaryotic species. The presented studies highlight the strength of combining low-resolution structure determination with biophysical and in silico modelling methods to extensively characterize proteins and their interactions. READ MORE