Search for dissertations about: "Conformational"
Showing result 1 - 5 of 468 swedish dissertations containing the word Conformational.
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1. Conformational Stability!? : Synthesis and Conformational Studies of Unnatural Backbone Modified Peptides
Abstract : The beauty of the wide functionality of proteins and peptides in Nature is determined by their ability to adopt three-dimensional structures. This thesis describes artificial molecules developed to mimic secondary structures similar to those found crucial for biological activities. READ MORE
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2. Susceptibility genes in conformational diseases
Abstract : Conformational diseases are characterized by protein misfolding and aggregation in the affected tissue. The aim of this thesis was to find genetic support for mechanisms in common for three prevalent ... READ MORE
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3. Asymmetric Catalysis : Ligand Design and Conformational Studies
Abstract : This thesis deals with the design of ligands for efficientasymmetric catalysis and studies of the conformation of theligands in the catalytically active complexes. All ligandsdeveloped contain chiral oxazoline heterocycles. READ MORE
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4. Assembling and Unraveling Carbohydrates Structures : Conformational analysis of synthesized branched oligosaccharides
Abstract : Advances in the elaboration of vaccines and enzyme inhibitors rely on acquiring more knowledge about protein-carbohydrate binding events. Furthermore, the relationships between biological function and the three-dimensional properties of large glycans can be studied by focusing on the structural components they contained, namely, by scaling down the system under analysis. READ MORE
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5. Deciphering Carbohydrate Structure : From NMR Chemical Shifts to Conformational Analysis
Abstract : Carbohydrates are ubiquitous in nature and exhibit a multitude of roles. Besides nucleic and amino acids, they can be regarded as the third alphabet of life. They are used as energy source to fuel the cells, as structural building blocks and play a key role in cellular recognition processes. READ MORE