Search for dissertations about: "Controlled cortical impact"

Showing result 1 - 5 of 13 swedish dissertations containing the words Controlled cortical impact.

  2. 1. Delayed Cell Death after Traumatic Brain Injury : Role of Reactive Oxygen Species

    Author : Fredrik Clausen; Lars Hillered; Tiit Mathiesen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Traumatic Brain Injury; Reactive oxygen species; Fluid percussion injury; Controlled cortical impact; weight drop injury; Extracellular-signal regulated kinase; apoptosis; free radical scavenging; morphology; functional outcome; Neurovetenskap; Neurology; Neurologi;

    Abstract : Traumatic brain injury (TBI) is a leading cause of death and disability TBI survivors often suffer from severe disturbances of cognition, memory and emotions. Improving the treatment is of great importance, but as of yet no specific neuroprotective treatment has been found. READ MORE

  4. 2. fMRI for mapping the plastic somatotopy of primary somatosensory cortex - Development and clinical applications

    Author : Andreas Weibull; Malmö Medicinsk strålningsfysik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; smoothing; physiological noise; spatial resolution; primary somatosensory cortex; cortical reorganisation; brain plasticity; fMRI; partial volume effects;

    Abstract : Functional magnetic resonance imaging (fMRI) is a widely used tool for studying brain function in vivo. The technique is based on acquiring brain images sensitive to the physiological response following neural activation, and hence, allows brain activity to be examined and documented. READ MORE

  5. 3. Effects of endocrine disruptors on adreno-cortical and Leydig cell steroidogenesis

    Author : Vichit Supornsilchai; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Endocrine disrupting chemicals EDCs ; steroidogenesis; Leydig cells; adrenocortical cells; steroidogenic acute regulatory protein StAR ; steroidogenic enzymes;

    Abstract : A common sequential pathway for steroidogenesis, designed to produce steroid hormones, is expressed in the adrenal cortex, testes and ovaries. In this process, cholesterol is converted to all known steroids by specific enzymes in a tissue-specific manner. READ MORE

  6. 4. Effects of Rho kinase, prostacyclin and L-arginine on microvascular permeability and perfusion

    Author : Cornelia Lundblad; Institutionen för immunteknologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fysiologi; Physiology; skeletal muscle; Rho kinase; prostacyclin; permeability; NO; experimental brain trauma; brain edema; brain contusion; microcirculation; cerebral perfusion;

    Abstract : This thesis presents some effects of Rho kinase, prostacyclin (PGI2) and nitric oxide (NO) in relation to trauma and inflammation by evaluating their effects on microvascular perfusion and permeability in mouse brain and in cat skeletal muscle. PGI2 and NO are endogenous vasoactive substances produced by the endothelium. READ MORE

  7. 5. Neural Stem and Progenitor Cells as a Tool for Tissue Regeneration

    Author : Ulrika Wallenquist; Karin Forsberg Nilsson; Lars Hillered; Karin Holmqvist; Anders Lewén; Johan Bengzon; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; traumatic brain injury; neural stem cells; transplantation; CNS; PNS; progenitor cells; inflammation; CCI; Biochemistry; Biokemi; Neurosurgery; neurokirurgi; Medical Biochemistry; medicinsk biokemi;

    Abstract : Neural stem and progenitor cells (NSPC) can differentiate to neurons and glial cells. NSPC are easily propagated in vitro and are therefore an attractive tool for tissue regeneration. Traumatic brain injury (TBI) is a common cause for death and disabilities. A fundamental problem following TBI is tissue loss. READ MORE