Search for dissertations about: "Cooperating Lesions"

Found 1 swedish dissertation containing the words Cooperating Lesions.

2. 1. Molecular Interrogation and Functional Studies of Acute Leukemia

   Author : Axel Hyrenius Wittsten; Avdelningen för klinisk genetik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acute leukemia; KMT2A; Cooperating Lesions; Clonal Relationship; Genomic Profiling; Fusion Genes;

   Abstract : Hematological malignancies are defined by their underlying genetic alterations, many of which are used to diagnose patients to classify them to different risk groups that dictate the therapy given. Recent advances in high-throughput sequencing have highlighted the presence of co-occurring genetic lesions and that they may form distinct genetic clones that evolve throughout disease progression. READ MORE