Search for dissertations about: "Cornea"

Showing result 1 - 5 of 52 swedish dissertations containing the word Cornea.

2. 1. Underlying genetic mechanisms of hereditary dystrophies in retina and cornea

   Author : Jonsson Frida; Irina Golovleva; Carlo Rivolta; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cornea; retina; gene; mutation detection; inherited diseases; genetik; Genetics;

   Abstract : Inherited retinal and corneal dystrophies represent a group of disorders with great genetic heterogeneity. Over 250 genes are associated with retinal diseases and 16 genes are causative of corneal dystrophies. READ MORE

4. 2. Ultraviolet radiation and cornea

   Author : Alexander Podskochy; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Cornea; UVR; keratocytes; apoptosis; Fas ligand; hyaluronan; biglycan; rabbit; wound healing.;

   Abstract : Background: Acute exposure of the mammalian eye to UVR results in development of photokeratitis after a period of a few hours. Chronic exposure to UVR is associated with an increased risk of several corneal disorders, including pterygium, climatic droplet keratopathy, and climatic proteoglycan stromal keratopathy. READ MORE

5. 3. Arachidonic acid metabolism in corneal epithelial cells : Identification of lipoxygenase isoforms

   Author : Maria Liminga; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biosciences; Cornea; cDNA cloning; lipoxygenase; liquid chromatography-mass spectrometry; organ culture; Farmaceutisk biovetenskap; Biopharmacy; Biofarmaci; farmaceutisk farmakologi; Pharmaceutical Pharmacology;

   Abstract : The metabolism of arachidonic acid in the human cornea was investigated and compared with the metabolism in cattle and primates. All three species showed significant arachidonic acid metabolism inthe epithelium, whereas the activity in the stroma and the endothelium was low or undetectable. READ MORE

6. 4. Cystatin C in the Eye and in Specific Model Systems

   Author : Johan Wasselius; Lund Institutionen för kliniska vetenskaper; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ophtalmology; protein uptake; ciliary body; lens; cornea; retina; eye; Cystatin C; cathepsin B; Oftalmologi;

   Abstract : It is a necessity of life to make proteins, and it is an equal necessity to degrade those proteins, to eliminate dysfunctional proteins, and leave room for new ones. The processes of protein synthesis and degradation into peptides - proteolysis - have attracted a great interest during the last decades. READ MORE

7. 5. Laminins and alpha11 integrin in the human eye : importance in development and disease

   Author : Berit Byström; Fatima Pedrosa Domellöf; Ulf Stenevi; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; basement membranes; extracellular matrix; laminin; integrin; cornea; development; keratoconus; wound healing; remodeling; immunohistochemistry; Ophtalmiatrics; Oftalmiatrik;

   Abstract : The extracellular matrix (ECM) offers a protective shelter for cells and provides signaling paths important for cell to cell communication. ECM consists of basement membranes (BM) and interstitial matrix. BMs provide mechanical support for parenchymal cells, influence cell proliferation, survival, migration and differentiation. READ MORE