Search for dissertations about: "Cowden disease"

Found 3 swedish dissertations containing the words Cowden disease.

2. 1. Molecular genetic studies of human thyroid tumors

   Author : Tony Frisk; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Follicular thyroid tumors; tumor progression; Cowden disease; PTEN; CGH; RET; medullary thyroid carcinoma; MEN 2; anaplastic carcinoma.;

   Abstract : Tumors of the thyroid gland are common among the general population, but only a small proportion is malignant. The vast majority of thyroid tumors are benign, so called follicular adenomas. Sometimes subtypes such as atypical adenomas and adenomas with oxyphil, i.e. READ MORE

4. 2. Next generation sequencing to find genetic risk factors in familial cancer

   Author : Jessada Thutkawkorapin; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : In 2015, Cancer is the second leading cause of death worldwide. Genetic predisposition in familial cancer cases is largely unexplained. At the same time, rapid development in sequencing technology results in an unprecedented increase in the amount of whole exome- and whole genome sequencing data. READ MORE

5. 3. Hereditary, molecular and prognostic factors in endometrial cancer

   Author : Ofra Castro Wersäll; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Aims: The overall aim of this thesis is to describe and evaluate hereditary uterine cancer syndrome both independent of and in relation to hereditary patterns of Lynch and/or Cowden syndrome for the purpose of recognizing and defining a unique pattern of familial uterine cancer. The thesis also aims to determine whether the TERT-CLPTM1L region is a novel risk locus for endometrial cancer. READ MORE