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Showing result 1 - 5 of 21 swedish dissertations matching the above criteria.
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1. Coxsackievirus B3 Infection and Host Defence Responses Change the Metabolism of PBDE
Abstract : It has been suggested that the rising amounts of chemicals in the environment may affect host resistance and increase susceptibility to infections. Studies have also shown that infections can change the toxicity of pollutants. READ MORE
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2. Arsenic Influences Virus Replication in Experimental Coxsackievirus B3 Infection
Abstract : Trace elements are essential for the host defence against infections, and during common infections, the balance of trace elements is changed in serum and tissues. Supplementation with selenium (Se), an essential trace element, is known to decrease the severity of coxsackievirus B3 (CVB3) infection in mice. READ MORE
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3. Metabolomic features and viral infections in paediatric inflammatory bowel disease
Abstract : Background: Up to 25% of patients with inflammatory bowel disease have a paediatric onset (PIBD). The pathophysiological processes underlying PIBD are complex and largely unknown. Aims: To investigate a hypothesized role for human enterovirus B (HEV-B) in Crohn’s disease (CD) (I). READ MORE
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4. Effects of Enterovirus Infection on Innate Immunity and Beta Cell Function in Human Islets of Langerhans
Abstract : This thesis focuses on enteroviral effects on human pancreatic islets. Most knowledge of viral effects on host cells relies on studies of immortalized cell lines or animal models. The islets represent a fundamentally different and less well studied cellular host. Also, enterovirus has been implicated in the etiology of type 1 diabetes (T1D). READ MORE
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5. Reverse genetic studies of Enterovirus replication
Abstract : Enteroviruses belong to the Picornaviridae family and are small icosahedral viruses with RNA genomes of positive polarity, containing a single open reading frame. They mostly cause mild or asymptomatic infections, but also a wide array of diseases including: poliomyelitis, encephalitis, gastroenteritis, aseptic meningitis, myocarditis, hand-foot-and-mouth disease, hepatitis and respiratory diseases, ranging from severe infections to the common cold. READ MORE